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PIAS1 potentiates the anti-EBV activity of SAMHD1 through SUMOylation

BACKGROUND: Sterile alpha motif and HD domain 1 (SAMHD1) is a deoxynucleotide triphosphohydrolase (dNTPase) that restricts the infection of a variety of RNA and DNA viruses, including herpesviruses. The anti-viral function of SAMHD1 is associated with its dNTPase activity, which is regulated by seve...

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Detalles Bibliográficos
Autores principales:	Saiada, Farjana, Zhang, Kun, Li, Renfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264492/ https://www.ncbi.nlm.nih.gov/pubmed/34238351 http://dx.doi.org/10.1186/s13578-021-00636-y

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