Pharmacokinetic Modeling of Morphine’s Effect on Plasma Concentrations of Ticagrelor and Its Metabolite in Healthy Volunteers

This study aimed to build a mathematical model describing the pharmacokinetics of ticagrelor and its active metabolite (AR-C124910XX) in a stable setting with concomitant administration of morphine. The model consists of a set of four differential equations prepared upon the available knowledge rega...

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Detalles Bibliográficos
Autores principales: Buszko, Katarzyna, Kubica, Krystian, Hobl, Eva-Luise, Adamski, Piotr, Wnuk, Kacper, Jilma, Bernd, Kubica, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264498/
https://www.ncbi.nlm.nih.gov/pubmed/34248659
http://dx.doi.org/10.3389/fphys.2021.663170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264498/
https://www.ncbi.nlm.nih.gov/pubmed/34248659
http://dx.doi.org/10.3389/fphys.2021.663170

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