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Nickel-Catcher-Doped Zwitterionic Hydrogel Coating on Nickel–Titanium Alloy Toward Capture and Detection of Nickel Ions
Nickel–titanium (NiTi) alloys show broad applicability in biomedical fields. However, the unexpected aggregation of bacteria and the corrosion of body fluid on NiTi-based medical devices often lead to the leakage of nickel ions, resulting in inevitable allergic and cytotoxic activities. Therefore, t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264594/ https://www.ncbi.nlm.nih.gov/pubmed/34249892 http://dx.doi.org/10.3389/fbioe.2021.698745 |
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author | Fu, Xiaoyi Liu, Xi Hao, Dezhao Xiao, Wuyi Nie, Qiong Meng, Jingxin |
author_facet | Fu, Xiaoyi Liu, Xi Hao, Dezhao Xiao, Wuyi Nie, Qiong Meng, Jingxin |
author_sort | Fu, Xiaoyi |
collection | PubMed |
description | Nickel–titanium (NiTi) alloys show broad applicability in biomedical fields. However, the unexpected aggregation of bacteria and the corrosion of body fluid on NiTi-based medical devices often lead to the leakage of nickel ions, resulting in inevitable allergic and cytotoxic activities. Therefore, the capture and detection of nickel ions are important to avoid serious adverse reactions caused by NiTi-based medical devices. Herein, we presented a nickel ion capture strategy by the combination of zwitterionic hydrogels as anti-bacteria layers and carbon disulfide (CS(2)) components as nickel-catchers (Ni-catchers). On the one hand, the hydration layer of zwitterionic hydrogel can efficiently inhibit bacteria adhesion and reduce nickel ions leakage from NiTi corrosion. On the other hand, Ni-catchers can capture leaked nickel ions from NiTi alloy actively by chelation reaction. Therefore, this strategy shows great capabilities in resisting bacteria adhesion and capturing nickel ions, providing the potential possibility for the detection of nickel ion leakage for implantable biomedical materials and devices. |
format | Online Article Text |
id | pubmed-8264594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82645942021-07-09 Nickel-Catcher-Doped Zwitterionic Hydrogel Coating on Nickel–Titanium Alloy Toward Capture and Detection of Nickel Ions Fu, Xiaoyi Liu, Xi Hao, Dezhao Xiao, Wuyi Nie, Qiong Meng, Jingxin Front Bioeng Biotechnol Bioengineering and Biotechnology Nickel–titanium (NiTi) alloys show broad applicability in biomedical fields. However, the unexpected aggregation of bacteria and the corrosion of body fluid on NiTi-based medical devices often lead to the leakage of nickel ions, resulting in inevitable allergic and cytotoxic activities. Therefore, the capture and detection of nickel ions are important to avoid serious adverse reactions caused by NiTi-based medical devices. Herein, we presented a nickel ion capture strategy by the combination of zwitterionic hydrogels as anti-bacteria layers and carbon disulfide (CS(2)) components as nickel-catchers (Ni-catchers). On the one hand, the hydration layer of zwitterionic hydrogel can efficiently inhibit bacteria adhesion and reduce nickel ions leakage from NiTi corrosion. On the other hand, Ni-catchers can capture leaked nickel ions from NiTi alloy actively by chelation reaction. Therefore, this strategy shows great capabilities in resisting bacteria adhesion and capturing nickel ions, providing the potential possibility for the detection of nickel ion leakage for implantable biomedical materials and devices. Frontiers Media S.A. 2021-06-24 /pmc/articles/PMC8264594/ /pubmed/34249892 http://dx.doi.org/10.3389/fbioe.2021.698745 Text en Copyright © 2021 Fu, Liu, Hao, Xiao, Nie and Meng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Fu, Xiaoyi Liu, Xi Hao, Dezhao Xiao, Wuyi Nie, Qiong Meng, Jingxin Nickel-Catcher-Doped Zwitterionic Hydrogel Coating on Nickel–Titanium Alloy Toward Capture and Detection of Nickel Ions |
title | Nickel-Catcher-Doped Zwitterionic Hydrogel Coating on Nickel–Titanium Alloy Toward Capture and Detection of Nickel Ions |
title_full | Nickel-Catcher-Doped Zwitterionic Hydrogel Coating on Nickel–Titanium Alloy Toward Capture and Detection of Nickel Ions |
title_fullStr | Nickel-Catcher-Doped Zwitterionic Hydrogel Coating on Nickel–Titanium Alloy Toward Capture and Detection of Nickel Ions |
title_full_unstemmed | Nickel-Catcher-Doped Zwitterionic Hydrogel Coating on Nickel–Titanium Alloy Toward Capture and Detection of Nickel Ions |
title_short | Nickel-Catcher-Doped Zwitterionic Hydrogel Coating on Nickel–Titanium Alloy Toward Capture and Detection of Nickel Ions |
title_sort | nickel-catcher-doped zwitterionic hydrogel coating on nickel–titanium alloy toward capture and detection of nickel ions |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264594/ https://www.ncbi.nlm.nih.gov/pubmed/34249892 http://dx.doi.org/10.3389/fbioe.2021.698745 |
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