MDM2 Binding Protein Induces the Resistance of Hepatocellular Carcinoma Cells to Molecular Targeting Agents via Enhancing the Transcription Factor Activity of the Pregnane X Receptor

The MDM2 binding protein (MTBP) has been considered an important regulator of human malignancies. In this study, we demonstrate that the high level of MTBP’s endogenous expression is correlated with poor prognosis of advanced hepatocellular carcinoma (HCC) patients who received sorafenib. MTBP inter...

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Detalles Bibliográficos
Autores principales: Jiang, Qiyu, Ma, Yan, Han, Jingjing, Chu, Jingdong, Ma, Xuemei, Shen, Lijun, Liu, Bo, Li, Bo-an, Hou, Jun, Bi, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264664/
https://www.ncbi.nlm.nih.gov/pubmed/34249768
http://dx.doi.org/10.3389/fonc.2021.715193

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