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Leptin and Melanocortin Signaling Mediates Hypertension in Offspring From Female Rabbits Fed a High-Fat Diet During Gestation and Lactation

Maternal high-fat diet in rabbits leads to hypertension and elevated renal sympathetic nerve activity (RSNA) in adult offspring but whether this is due to adiposity or maternal programming is unclear. We gave intracerebroventricular (ICV) and ventromedial hypothalamus (VMH) administration of leptin-...

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Autores principales:	Lim, Kyungjoon, Burke, Sandra L., Marques, Francine Z., Jackson, Kristy L., Gueguen, Cindy, Sata, Yusuke, Armitage, James A., Head, Geoffrey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264761/ https://www.ncbi.nlm.nih.gov/pubmed/34248679 http://dx.doi.org/10.3389/fphys.2021.693157

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