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SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway

Spinster homologue 2 (SPNS2), a transporter of S1P (sphingosine-1-phosphate), has been reported to mediate immune response, vascular development, and pathologic processes of diseases such as cancer via S1P signaling pathways. However, its biological functions and expression profile in colorectal can...

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Detalles Bibliográficos
Autores principales: Lv, Lei, Yi, Qiyi, Yan, Ying, Chao, Fengmei, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264774/
https://www.ncbi.nlm.nih.gov/pubmed/34249729
http://dx.doi.org/10.3389/fonc.2021.682773