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Effects of the Local Bone Renin-Angiotensin System on Titanium-Particle-Induced Periprosthetic Osteolysis

Wear particles may induce osteoclast formation and osteoblast inhibition that lead to periprosthetic osteolysis (PPOL) and subsequent aseptic loosening, which is the primary reason for total joint arthroplasty failure. Local bone renin-angiotensin system (RAS) has been found to participate in the pa...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhiping, Wang, Changyao, Xu, Yingxing, Wang, Xiangyu, Jia, Bin, Yu, Tengbo, Wang, Yingzhen, Zhang, Yongtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264785/ https://www.ncbi.nlm.nih.gov/pubmed/34248634 http://dx.doi.org/10.3389/fphar.2021.684375

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