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Identification of Suicidal Ideation in the Canadian Community Health Survey—Mental Health Component Using Deep Learning

Introduction: Suicidal ideation (SI) is prevalent in the general population, and is a risk factor for suicide. Predicting which patients are likely to have SI remains challenging. Deep Learning (DL) may be a useful tool in this context, as it can be used to find patterns in complex, heterogeneous, a...

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Autores principales: Desai, Sneha, Tanguay-Sela, Myriam, Benrimoh, David, Fratila, Robert, Brown, Eleanor, Perlman, Kelly, John, Ann, DelPozo-Banos, Marcos, Low, Nancy, Israel, Sonia, Palladini, Lisa, Turecki, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264793/
https://www.ncbi.nlm.nih.gov/pubmed/34250463
http://dx.doi.org/10.3389/frai.2021.561528
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author Desai, Sneha
Tanguay-Sela, Myriam
Benrimoh, David
Fratila, Robert
Brown, Eleanor
Perlman, Kelly
John, Ann
DelPozo-Banos, Marcos
Low, Nancy
Israel, Sonia
Palladini, Lisa
Turecki, Gustavo
author_facet Desai, Sneha
Tanguay-Sela, Myriam
Benrimoh, David
Fratila, Robert
Brown, Eleanor
Perlman, Kelly
John, Ann
DelPozo-Banos, Marcos
Low, Nancy
Israel, Sonia
Palladini, Lisa
Turecki, Gustavo
author_sort Desai, Sneha
collection PubMed
description Introduction: Suicidal ideation (SI) is prevalent in the general population, and is a risk factor for suicide. Predicting which patients are likely to have SI remains challenging. Deep Learning (DL) may be a useful tool in this context, as it can be used to find patterns in complex, heterogeneous, and incomplete datasets. An automated screening system for SI could help prompt clinicians to be more attentive to patients at risk for suicide. Methods: Using the Canadian Community Health Survey—Mental Health Component, we trained a DL model based on 23,859 survey responses to classify patients with and without SI. Models were created to classify both lifetime SI and SI over the last 12 months. From 582 possible parameters we produced 96- and 21-feature versions of the models. Models were trained using an undersampling procedure that balanced the training set between SI and non-SI; validation was done on held-out data. Results: For lifetime SI, the 96 feature model had an Area under the receiver operating curve (AUC) of 0.79 and the 21 feature model had an AUC of 0.77. For SI in the last 12 months the 96 feature model had an AUC of 0.71 and the 21 feature model had an AUC of 0.68. In addition, sensitivity analyses demonstrated feature relationships in line with existing literature. Discussion: Although further study is required to ensure clinical relevance and sample generalizability, this study is an initial proof of concept for the use of DL to improve identification of SI. Sensitivity analyses can help improve the interpretability of DL models. This kind of model would help start conversations with patients which could lead to improved care and a reduction in suicidal behavior.
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spelling pubmed-82647932021-07-09 Identification of Suicidal Ideation in the Canadian Community Health Survey—Mental Health Component Using Deep Learning Desai, Sneha Tanguay-Sela, Myriam Benrimoh, David Fratila, Robert Brown, Eleanor Perlman, Kelly John, Ann DelPozo-Banos, Marcos Low, Nancy Israel, Sonia Palladini, Lisa Turecki, Gustavo Front Artif Intell Artificial Intelligence Introduction: Suicidal ideation (SI) is prevalent in the general population, and is a risk factor for suicide. Predicting which patients are likely to have SI remains challenging. Deep Learning (DL) may be a useful tool in this context, as it can be used to find patterns in complex, heterogeneous, and incomplete datasets. An automated screening system for SI could help prompt clinicians to be more attentive to patients at risk for suicide. Methods: Using the Canadian Community Health Survey—Mental Health Component, we trained a DL model based on 23,859 survey responses to classify patients with and without SI. Models were created to classify both lifetime SI and SI over the last 12 months. From 582 possible parameters we produced 96- and 21-feature versions of the models. Models were trained using an undersampling procedure that balanced the training set between SI and non-SI; validation was done on held-out data. Results: For lifetime SI, the 96 feature model had an Area under the receiver operating curve (AUC) of 0.79 and the 21 feature model had an AUC of 0.77. For SI in the last 12 months the 96 feature model had an AUC of 0.71 and the 21 feature model had an AUC of 0.68. In addition, sensitivity analyses demonstrated feature relationships in line with existing literature. Discussion: Although further study is required to ensure clinical relevance and sample generalizability, this study is an initial proof of concept for the use of DL to improve identification of SI. Sensitivity analyses can help improve the interpretability of DL models. This kind of model would help start conversations with patients which could lead to improved care and a reduction in suicidal behavior. Frontiers Media S.A. 2021-06-24 /pmc/articles/PMC8264793/ /pubmed/34250463 http://dx.doi.org/10.3389/frai.2021.561528 Text en Copyright © 2021 Desai, Tanguay-Sela, Benrimoh, Fratila, Brown, Perlman, John, DelPozo-Banos, Low, Israel, Palladini and Turecki. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Artificial Intelligence
Desai, Sneha
Tanguay-Sela, Myriam
Benrimoh, David
Fratila, Robert
Brown, Eleanor
Perlman, Kelly
John, Ann
DelPozo-Banos, Marcos
Low, Nancy
Israel, Sonia
Palladini, Lisa
Turecki, Gustavo
Identification of Suicidal Ideation in the Canadian Community Health Survey—Mental Health Component Using Deep Learning
title Identification of Suicidal Ideation in the Canadian Community Health Survey—Mental Health Component Using Deep Learning
title_full Identification of Suicidal Ideation in the Canadian Community Health Survey—Mental Health Component Using Deep Learning
title_fullStr Identification of Suicidal Ideation in the Canadian Community Health Survey—Mental Health Component Using Deep Learning
title_full_unstemmed Identification of Suicidal Ideation in the Canadian Community Health Survey—Mental Health Component Using Deep Learning
title_short Identification of Suicidal Ideation in the Canadian Community Health Survey—Mental Health Component Using Deep Learning
title_sort identification of suicidal ideation in the canadian community health survey—mental health component using deep learning
topic Artificial Intelligence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264793/
https://www.ncbi.nlm.nih.gov/pubmed/34250463
http://dx.doi.org/10.3389/frai.2021.561528
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