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The timing of adrenarche in Maya girls, Merida, Mexico

BACKGROUND: Adrenarche involves maturation of the hypothalamic‐pituitary‐adrenal axis and increased production of dehydroepiandrosterone and its sulfate ester, dehydroepiandrosterone‐sulfate (DHEA‐S). It occurs at ages 6 to 8 in industrialized populations, marking the transition from childhood to ju...

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Autores principales: Keestra, Sarai M., Bentley, Gillian R., Núñez‐de la Mora, Alejandra, Houghton, Lauren C., Wilson, Hannah, Vázquez‐Vázquez, Adriana, Cooper, Gillian D., Dickinson, Federico, Griffiths, Paula, Bogin, Barry A., Varela‐Silva, Maria Inês
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264844/
https://www.ncbi.nlm.nih.gov/pubmed/32643208
http://dx.doi.org/10.1002/ajhb.23465
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author Keestra, Sarai M.
Bentley, Gillian R.
Núñez‐de la Mora, Alejandra
Houghton, Lauren C.
Wilson, Hannah
Vázquez‐Vázquez, Adriana
Cooper, Gillian D.
Dickinson, Federico
Griffiths, Paula
Bogin, Barry A.
Varela‐Silva, Maria Inês
author_facet Keestra, Sarai M.
Bentley, Gillian R.
Núñez‐de la Mora, Alejandra
Houghton, Lauren C.
Wilson, Hannah
Vázquez‐Vázquez, Adriana
Cooper, Gillian D.
Dickinson, Federico
Griffiths, Paula
Bogin, Barry A.
Varela‐Silva, Maria Inês
author_sort Keestra, Sarai M.
collection PubMed
description BACKGROUND: Adrenarche involves maturation of the hypothalamic‐pituitary‐adrenal axis and increased production of dehydroepiandrosterone and its sulfate ester, dehydroepiandrosterone‐sulfate (DHEA‐S). It occurs at ages 6 to 8 in industrialized populations, marking the transition from childhood to juvenility and cognitive development at middle childhood. Studies in subsistence level populations indicate a later age (8‐9) for adrenarche, but only two such studies currently exist for comparison. AIMS: To investigate adrenarcheal age among Maya girls and its association with body composition and dietary variables. We hypothesized adrenarche would occur earlier given the current dual burden of nutrition in Mexico. MATERIALS AND METHODS: 25 Maya girls aged 7 to 9 from Merida, Mexico using ELISAs to measure salivary DHEA‐S, standard anthropometry for height, weight, and skinfolds, bioelectrical impedance for body composition variables, as well as a food frequency questionnaire for dietary information. RESULTS: Our hypothesis was rejected—adrenarche occurred close to 9 years. While no measures of body composition were significantly associated with adrenarcheal status, girls eating meat and dairy products more frequently had significantly higher DHEA‐S levels. DISCUSSION: Like other populations living in ecologically challenging environments, adrenarche occurred relatively late among Maya girls. Adrenarche has been linked to measures of body composition, particularly, the adiposity or body mass index rebound, but no relevant anthropometric measures were associated, possibly because of the small sample. CONCLUSION: Further studies are required to illuminate how adrenarcheal variation relates to developmental plasticity, body composition, pubertal progression, and animal product consumption in other transitional populations.
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spelling pubmed-82648442021-07-13 The timing of adrenarche in Maya girls, Merida, Mexico Keestra, Sarai M. Bentley, Gillian R. Núñez‐de la Mora, Alejandra Houghton, Lauren C. Wilson, Hannah Vázquez‐Vázquez, Adriana Cooper, Gillian D. Dickinson, Federico Griffiths, Paula Bogin, Barry A. Varela‐Silva, Maria Inês Am J Hum Biol Short Reports BACKGROUND: Adrenarche involves maturation of the hypothalamic‐pituitary‐adrenal axis and increased production of dehydroepiandrosterone and its sulfate ester, dehydroepiandrosterone‐sulfate (DHEA‐S). It occurs at ages 6 to 8 in industrialized populations, marking the transition from childhood to juvenility and cognitive development at middle childhood. Studies in subsistence level populations indicate a later age (8‐9) for adrenarche, but only two such studies currently exist for comparison. AIMS: To investigate adrenarcheal age among Maya girls and its association with body composition and dietary variables. We hypothesized adrenarche would occur earlier given the current dual burden of nutrition in Mexico. MATERIALS AND METHODS: 25 Maya girls aged 7 to 9 from Merida, Mexico using ELISAs to measure salivary DHEA‐S, standard anthropometry for height, weight, and skinfolds, bioelectrical impedance for body composition variables, as well as a food frequency questionnaire for dietary information. RESULTS: Our hypothesis was rejected—adrenarche occurred close to 9 years. While no measures of body composition were significantly associated with adrenarcheal status, girls eating meat and dairy products more frequently had significantly higher DHEA‐S levels. DISCUSSION: Like other populations living in ecologically challenging environments, adrenarche occurred relatively late among Maya girls. Adrenarche has been linked to measures of body composition, particularly, the adiposity or body mass index rebound, but no relevant anthropometric measures were associated, possibly because of the small sample. CONCLUSION: Further studies are required to illuminate how adrenarcheal variation relates to developmental plasticity, body composition, pubertal progression, and animal product consumption in other transitional populations. John Wiley & Sons, Inc. 2020-07-09 2021 /pmc/articles/PMC8264844/ /pubmed/32643208 http://dx.doi.org/10.1002/ajhb.23465 Text en © 2020 The Authors. American Journal of Human Biology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Reports
Keestra, Sarai M.
Bentley, Gillian R.
Núñez‐de la Mora, Alejandra
Houghton, Lauren C.
Wilson, Hannah
Vázquez‐Vázquez, Adriana
Cooper, Gillian D.
Dickinson, Federico
Griffiths, Paula
Bogin, Barry A.
Varela‐Silva, Maria Inês
The timing of adrenarche in Maya girls, Merida, Mexico
title The timing of adrenarche in Maya girls, Merida, Mexico
title_full The timing of adrenarche in Maya girls, Merida, Mexico
title_fullStr The timing of adrenarche in Maya girls, Merida, Mexico
title_full_unstemmed The timing of adrenarche in Maya girls, Merida, Mexico
title_short The timing of adrenarche in Maya girls, Merida, Mexico
title_sort timing of adrenarche in maya girls, merida, mexico
topic Short Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264844/
https://www.ncbi.nlm.nih.gov/pubmed/32643208
http://dx.doi.org/10.1002/ajhb.23465
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