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Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial

INTRODUCTION: Septic shock is the subgroup of patients with sepsis, which presents as vasopressor dependence, an elevated blood lactate concentration and is associated with a mortality of at least 30%. Expression of the triggering receptor expressed on myeloid cells 1 (TREM-1) pathway, measured usin...

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Autores principales:	Francois, Bruno, Lambden, Simon, Gibot, Sebastien, Derive, Marc, Olivier, Aurelie, Cuvier, Valerie, Witte, Stephan, Grouin, Jean-Marie, Garaud, Jean Jacques, Salcedo-Magguilli, Margarita, Levy, Mitchell, Laterre, Pierre-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Intensive Care
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264912/ https://www.ncbi.nlm.nih.gov/pubmed/34233965 http://dx.doi.org/10.1136/bmjopen-2020-042921

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