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Effects of infliximab on lung and circulating natural killer cells, CD56+ T cells and B cells in sarcoidosis

BACKGROUND: Tumour necrosis factor α (TNF-α) is pivotal in sarcoid granuloma formation, and inhibitors of TNF-α offer an attractive third-line treatment option in sarcoidosis. The sarcoid inflammation is characterised by an exaggerated T helper 1 response, and evidence indicates a contribution of dy...

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Detalles Bibliográficos
Autores principales: Kullberg, Susanna, Rivera, Natalia V, Grunewald, Johan, Eklund, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264913/
https://www.ncbi.nlm.nih.gov/pubmed/34233893
http://dx.doi.org/10.1136/bmjresp-2021-000933