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OTEH-2. High-dimensional analysis of spatial immune cell heterogeneity in glioblastoma reveals differences between contrast-enhancing and non-contrast-enhancing tumor rims
BACKGROUND: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. GBM remains an incurable disease, with a median survival ~20 months. Complex intercellular interactions within the tumor microenvironment and spatial heterogeneity have challenged and impeded therapeutic effic...
Autores principales: | Watson, Dionysios C, Bayik, Defne, Grabowski, Matthew, Ahluwalia, Manmeet, Mohammadi, Alireza, Lathia, Justin D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264919/ http://dx.doi.org/10.1093/noajnl/vdab070.041 |
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