Cargando…
Characterization of the Metabolic Pathways of 4-Chlorobiphenyl (PCB3) in HepG2 Cells Using the Metabolite Profiles of Its Hydroxylated Metabolites
[Image: see text] The characterization of the metabolism of lower chlorinated PCB, such as 4-chlorobiphenyl (PCB3), is challenging because of the complex metabolite mixtures formed in vitro and in vivo. We performed parallel metabolism studies with PCB3 and its hydroxylated metabolites to characteri...
Autores principales: | Zhang, Chun-Yun, Flor, Susanne, Ruiz, Patricia, Ludewig, Gabriele, Lehmler, Hans-Joachim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264946/ https://www.ncbi.nlm.nih.gov/pubmed/34125531 http://dx.doi.org/10.1021/acs.est.1c01076 |
Ejemplares similares
-
Metabolism of 3-Chlorobiphenyl
(PCB 2) in a
Human-Relevant Cell Line: Evidence of Dechlorinated Metabolites
por: Zhang, Chun-Yun, et al.
Publicado: (2022) -
Disposition of Phenolic and
Sulfated Metabolites after
Inhalation Exposure to 4-Chlorobiphenyl (PCB3) in Female Rats
por: Dhakal, Kiran, et al.
Publicado: (2014) -
2,2′,3,5′,6-Pentachlorobiphenyl
(PCB
95) Is Atropselectively Metabolized to para-Hydroxylated Metabolites
by Human Liver Microsomes
por: Uwimana, Eric, et al.
Publicado: (2016) -
Microsomal
Oxidation of 2,2′,3,3′,6,6′-Hexachlorobiphenyl
(PCB 136) Results in Species-Dependent Chiral Signatures of the Hydroxylated
Metabolites
por: Wu, Xianai, et al.
Publicado: (2014) -
Selective retention of hydroxylated PCB metabolites in blood.
por: Bergman, A, et al.
Publicado: (1994)