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Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl
Synovial sarcoma is a soft tissue sarcoma. Its occurrence as a primary mediastinal neoplasm is very rare. We report a case of mediastinal synovial sarcoma in a 14‐year‐old girl with exertive dyspnoea at presentation. On physical examination, there was a superior vena cava syndrome and café‐au‐lait s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264954/ https://www.ncbi.nlm.nih.gov/pubmed/34262776 http://dx.doi.org/10.1002/rcr2.811 |
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author | Saad, Asma Bouacida, Imen Ben Radhia, Bechir Zribi, Hazem Dridi, Amira Marghli, Adel |
author_facet | Saad, Asma Bouacida, Imen Ben Radhia, Bechir Zribi, Hazem Dridi, Amira Marghli, Adel |
author_sort | Saad, Asma |
collection | PubMed |
description | Synovial sarcoma is a soft tissue sarcoma. Its occurrence as a primary mediastinal neoplasm is very rare. We report a case of mediastinal synovial sarcoma in a 14‐year‐old girl with exertive dyspnoea at presentation. On physical examination, there was a superior vena cava syndrome and café‐au‐lait spots. Chest X‐ray revealed a white left hemithorax with mediastinal deviation to the opposite side. Thoraco‐abdomino‐pelvic scanner showed a voluminous posterior cervico‐mediastinal tissue mass. Computed tomography (CT)‐guided biopsy of the mediastino‐pleural mass was performed. Histological examination reported fusocellular malignant mesenchymal proliferation. A complementary immunohistological study with a broad range of antibodies was performed with a high‐grade single‐phase spindle cell synovial sarcoma of the mediastinum. She presented a respiratory distress, did not respond to resuscitation, and died. Mediastinal synovial sarcoma is a rare tumour that is difficult to diagnose. Its slow progression and delay in diagnosis may lead to a fatal evolution. |
format | Online Article Text |
id | pubmed-8264954 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-82649542021-07-13 Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl Saad, Asma Bouacida, Imen Ben Radhia, Bechir Zribi, Hazem Dridi, Amira Marghli, Adel Respirol Case Rep Case Reports Synovial sarcoma is a soft tissue sarcoma. Its occurrence as a primary mediastinal neoplasm is very rare. We report a case of mediastinal synovial sarcoma in a 14‐year‐old girl with exertive dyspnoea at presentation. On physical examination, there was a superior vena cava syndrome and café‐au‐lait spots. Chest X‐ray revealed a white left hemithorax with mediastinal deviation to the opposite side. Thoraco‐abdomino‐pelvic scanner showed a voluminous posterior cervico‐mediastinal tissue mass. Computed tomography (CT)‐guided biopsy of the mediastino‐pleural mass was performed. Histological examination reported fusocellular malignant mesenchymal proliferation. A complementary immunohistological study with a broad range of antibodies was performed with a high‐grade single‐phase spindle cell synovial sarcoma of the mediastinum. She presented a respiratory distress, did not respond to resuscitation, and died. Mediastinal synovial sarcoma is a rare tumour that is difficult to diagnose. Its slow progression and delay in diagnosis may lead to a fatal evolution. John Wiley & Sons, Ltd 2021-07-08 /pmc/articles/PMC8264954/ /pubmed/34262776 http://dx.doi.org/10.1002/rcr2.811 Text en © 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Reports Saad, Asma Bouacida, Imen Ben Radhia, Bechir Zribi, Hazem Dridi, Amira Marghli, Adel Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl |
title | Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl |
title_full | Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl |
title_fullStr | Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl |
title_full_unstemmed | Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl |
title_short | Primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl |
title_sort | primary synovial sarcoma of the mediastinum: a poor prognosis in a 14‐year‐old girl |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264954/ https://www.ncbi.nlm.nih.gov/pubmed/34262776 http://dx.doi.org/10.1002/rcr2.811 |
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