Suppression of Adenosine Deaminase and Xanthine Oxidase Activities by Mineralocorticoid and Glucocorticoid Receptor Blockades Restores Renal Antioxidative Barrier in Oral Contraceptive-Treated Dam

OBJECTIVE: We tested the hypothesis that postpartum combined oral contraceptive (COC) treatment would induce oxidative stress via the adenosine deaminase-xanthine oxidase pathway in the kidney. We also sought to determine whether mineralocorticoid receptor (MR) or glucocorticoid receptor (GR ) block...

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Detalles Bibliográficos
Autores principales: Badmus, Olufunto O., Areola, Emmanuel D., Benjamin, Eleojo, Obekpa, Matthew A., Adegoke, Tolulope E., Elijah, Oluwatobi E., Imam, Aminu, Olajide, Olayemi J., Olatunji, Lawrence A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265027/
https://www.ncbi.nlm.nih.gov/pubmed/34285713
http://dx.doi.org/10.1155/2021/9966372

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