Cargando…

Dissecting immune cell stat regulation network reveals biomarkers to predict ICB therapy responders in melanoma

BACKGROUND: Immunotherapy is a revolutionary strategy in cancer therapy, but the resistance of which is one of the important challenges. Detecting the regulation of immune cells and biomarkers concerning immune checkpoint blockade (ICB) therapy is of great significance. METHODS: Here, we firstly con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jingwen, Li, Feng, Xu, Yanjun, Zheng, Xuan, Zhang, Chunlong, Hu, Congxue, Xu, Yingqi, Mi, Wanqi, Li, Xia, Zhang, Yunpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265039/ https://www.ncbi.nlm.nih.gov/pubmed/34238310 http://dx.doi.org/10.1186/s12967-021-02962-8

Ejemplares similares

Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data
por: Xu, Yanjun, et al.
Publicado: (2022)

Identifying and characterizing drug sensitivity-related lncRNA-TF-gene regulatory triplets
por: Hu, Congxue, et al.
Publicado: (2022)

Identifying subpathway signatures for individualized anticancer drug response by integrating multi-omics data
por: Xu, Yanjun, et al.
Publicado: (2019)

Quantifying Risk Pathway Crosstalk Mediated by miRNA to Screen Precision drugs for Breast Cancer Patients
por: Xu, Yingqi, et al.
Publicado: (2019)

Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma
por: Zhang, Chunlong, et al.
Publicado: (2022)

IPMA-D based on ICB 4 courseware
por: Hermarij, John
Publicado: (2017)

The Chemokines Initiating and Maintaining Immune Hot Phenotype Are Prognostic in ICB of HNSCC
por: Huang, Yuhong, et al.
Publicado: (2022)

MAOI Antidepressants: Could They Be a Next-Generation ICB Therapy?
por: Brown, James, et al.
Publicado: (2022)

Neutrophil‐Mediated Tumor‐Targeting Delivery System of Oncolytic Bacteria Combined with ICB for Melanoma Lung Metastasis Therapy
por: Liu, Lina, et al.
Publicado: (2023)

Prognostic Features of the Tumor Immune Microenvironment in Glioma and Their Clinical Applications: Analysis of Multiple Cohorts
por: Zhang, Chunlong, et al.
Publicado: (2022)

Evaluation safety and efficacy of immune checkpoint blockers (ICB) and radiotherapy combination versus ICB in non‐small cell lung cancer patients with recurrence or metastasis: A systematic review and meta‐analysis
por: Zeng, Yichun, et al.
Publicado: (2023)

Genetic diversity of Plasmodium Vivax revealed by the merozoite surface protein-1 icb5-6 fragment
por: Ruan, Wei, et al.
Publicado: (2017)

Integrating gene and lncRNA expression to infer subpathway activity for tumor analyses
por: Zhang, Chunlong, et al.
Publicado: (2017)

LncSubpathway: a novel approach for identifying dysfunctional subpathways associated with risk lncRNAs by integrating lncRNA and mRNA expression profiles and pathway topologies
por: Xu, Yanjun, et al.
Publicado: (2017)

A new ICB sister journal focuses on clinical and translational immunology
por: Belz, Gabrielle, et al.
Publicado: (2012)

Icb-1 gene polymorphism rs1467465 is associated with susceptibility to ovarian cancer
por: Schüler, Susanne, et al.
Publicado: (2014)

How intramolecular coordination bonding (ICB) controls the homolysis of the C–ON bond in alkoxyamines
por: Audran, Gérard, et al.
Publicado: (2019)

CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data
por: Hu, Congxue, et al.
Publicado: (2022)

Epitranscriptomic Approach: To Improve the Efficacy of ICB Therapy by Co-Targeting Intracellular Checkpoint CISH
por: Kumar, Sunil, et al.
Publicado: (2021)

Advances in biometrics: international conference, ICB 2007, Seoul, Korea, August 27-29, 2007, proceedings
por: Lee, Seong-Whan, et al.
Publicado: (2007)

Dissecting dysfunctional crosstalk pathways regulated by miRNAs during glioma progression
por: Zhang, Yunpeng, et al.
Publicado: (2016)

Going above and beyond for implementation: the development and validity testing of the Implementation Citizenship Behavior Scale (ICBS)
por: Ehrhart, Mark G, et al.
Publicado: (2015)

MiRSEA: Discovering the pathways regulated by dysfunctional MicroRNAs
por: Han, Junwei, et al.
Publicado: (2016)

Detection of Serotype-Specific Antibodies to the Four Dengue Viruses Using an Immune Complex Binding (ICB) ELISA
por: Emmerich, Petra, et al.
Publicado: (2013)

Treating ICB-resistant glioma with anti-CD40 and mitotic spindle checkpoint controller BAL101553 (lisavanbulin)
por: Genoud, Vassilis, et al.
Publicado: (2021)

Identification of Subtype Specific miRNA-mRNA Functional Regulatory Modules in Matched miRNA-mRNA Expression Data: Multiple Myeloma as a Case
por: Zhang, Yunpeng, et al.
Publicado: (2015)

Subpathway-LNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNA-mRNA expression profile and pathway topologies
por: Shi, Xinrui, et al.
Publicado: (2016)

Comprehensive analysis of mRNA‐level and miRNA‐level subpathway activities for identifying robust ovarian cancer prognostic signatures
por: Tian, Songyu, et al.
Publicado: (2020)

Themis2/ICB1 Is a Signaling Scaffold That Selectively Regulates Macrophage Toll-Like Receptor Signaling and Cytokine Production
por: Peirce, Matthew J., et al.
Publicado: (2010)

POSTN Secretion by Extracellular Matrix Cancer-Associated Fibroblasts (eCAFs) Correlates with Poor ICB Response via Macrophage Chemotaxis Activation of Akt Signaling Pathway in Gastric Cancer
por: You, Tingting, et al.
Publicado: (2023)

Prioritizing Candidate Disease Metabolites Based on Global Functional Relationships between Metabolites in the Context of Metabolic Pathways
por: Shang, Desi, et al.
Publicado: (2014)

PRSS1 Upregulation Predicts Platinum Resistance in Ovarian Cancer Patients
por: Xing, Linan, et al.
Publicado: (2021)

Comprehensive analyses of brain cell communications based on multiple scRNA‐seq and snRNA‐seq datasets for revealing novel mechanism in neurodegenerative diseases
por: Zhang, Chunlong, et al.
Publicado: (2023)

The LncRNA Connectivity Map: Using LncRNA Signatures to Connect Small Molecules, LncRNAs, and Diseases
por: Yang, Haixiu, et al.
Publicado: (2017)

High levels of IgG3 anti ICB2-5 in Plasmodium vivax-infected individuals who did not develop symptoms
por: Versiani, Fernanda G, et al.
Publicado: (2013)

System level characterization of small molecule drugs and their affected long noncoding RNAs
por: Yang, Haixiu, et al.
Publicado: (2019)

Subpathway-GMir: identifying miRNA-mediated metabolic subpathways by integrating condition-specific genes, microRNAs, and pathway topologies
por: Feng, Li, et al.
Publicado: (2015)

Detection of antibodies against the CB9 to ICB10 region of merozoite surface protein-1 of Plasmodium vivax among the inhabitants in epidemic areas
por: Kim, Tong-Soo, et al.
Publicado: (2014)

BioM2MetDisease: a manually curated database for associations between microRNAs, metabolites, small molecules and metabolic diseases
por: Xu, Yanjun, et al.
Publicado: (2017)

LncRNAs2Pathways: Identifying the pathways influenced by a set of lncRNAs of interest based on a global network propagation method
por: Han, Junwei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ksuu4erhka1uln1hhp8vn4lnjl