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PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing
Prime editing technology is capable of generating targeted insertions, deletions, and base conversions. However, the process of designing prime editing guide RNAs (pegRNAs), which contain a primer binding site and a reverse-transcription template at the 3′ end, is more complex than that for the sing...
Autores principales: | Hwang, Gue-Ho, Jeong, You Kyeong, Habib, Omer, Hong, Sung-Ah, Lim, Kayeong, Kim, Jin-Soo, Bae, Sangsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265102/ https://www.ncbi.nlm.nih.gov/pubmed/33939828 http://dx.doi.org/10.1093/nar/gkab319 |
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