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pegIT - a web-based design tool for prime editing
Prime editing (PE) is a novel CRISPR-derived genome editing technique facilitating precision editing without double-stranded DNA breaks. PE, mediated by a Cas9-reverse transcriptase fusion protein, is based on dual-functioning prime editing guide RNAs (pegRNAs), serving both as guide molecules and a...
Autores principales: | Anderson, Mads Valdemar, Haldrup, Jakob, Thomsen, Emil Aagaard, Wolff, Jonas Holst, Mikkelsen, Jacob Giehm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265180/ https://www.ncbi.nlm.nih.gov/pubmed/34060619 http://dx.doi.org/10.1093/nar/gkab427 |
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