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Prevalence of Five Pharmacologically Most Important CYP2C9 and CYP2C19 Allelic Variants in the Population from the Republic of Srpska in Bosnia and Herzegovina
The enzymes of the cytochrome P450 superfamily play a critical role in phase I drug metabolism. Among them, CYP2C9 and CYP2C19 are clinically important, as they can mediate severe toxicity, therapy failure, and increased susceptibility to cancer and other diseases caused by chemicals. The aim of thi...
Autores principales: | Vidović, Stojko, Škrbić, Ranko, Stojiljković, Miloš P., Vidović, Vanja, Bećarević, Jelena, Stoisavljević-Šatara, Svjetlana, Maksimović, Nela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sciendo
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265196/ https://www.ncbi.nlm.nih.gov/pubmed/34187105 http://dx.doi.org/10.2478/aiht-2021-72-3499 |
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