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Cardiomyocyte Deletion of Bmal1 Exacerbates QT- and RR-Interval Prolongation in Scn5a(+/ΔKPQ) Mice
Circadian rhythms are generated by cell autonomous circadian clocks that perform a ubiquitous cellular time-keeping function and cell type-specific functions important for normal physiology. Studies show inducing the deletion of the core circadian clock transcription factor Bmal1 in adult mouse card...
Autores principales: | Schroder, Elizabeth A., Wayland, Jennifer L., Samuels, Kaitlyn M., Shah, Syed F., Burgess, Don E., Seward, Tanya, Elayi, Claude S., Esser, Karyn A., Delisle, Brian P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265216/ https://www.ncbi.nlm.nih.gov/pubmed/34248669 http://dx.doi.org/10.3389/fphys.2021.681011 |
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