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Collateral Sensitivity to β-Lactam Drugs in Drug-Resistant Tuberculosis Is Driven by the Transcriptional Wiring of BlaI Operon Genes

The evolution of resistance to one antimicrobial can result in enhanced sensitivity to another, known as “collateral sensitivity.” This underexplored phenomenon opens new therapeutic possibilities for patients infected with pathogens unresponsive to classical treatments. Intrinsic resistance to β-la...

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Detalles Bibliográficos
Autores principales:	Trigos, A. S., Goudey, B. W., Bedő, J., Conway, T. C., Faux, N. G., Wyres, K. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265638/ https://www.ncbi.nlm.nih.gov/pubmed/34047652 http://dx.doi.org/10.1128/mSphere.00245-21

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