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Adult Wilms' Tumor: Case Report and Literature Review

Wilms' tumor is childhood’s most common renal tumor, and its presentation in the adult age is extremely rare. Due to the low frequency in adults, no standard management guidelines are available for this population, also the natural history of the disease and management is unclear. We present a...

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Autores principales: Vallejo Yepes, Camilo, Bermudez, Marcela, Camacho-Nieto, Diego, Mesa, Jorge, Bruges, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265692/
https://www.ncbi.nlm.nih.gov/pubmed/34268047
http://dx.doi.org/10.7759/cureus.15524
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author Vallejo Yepes, Camilo
Bermudez, Marcela
Camacho-Nieto, Diego
Mesa, Jorge
Bruges, Ricardo
author_facet Vallejo Yepes, Camilo
Bermudez, Marcela
Camacho-Nieto, Diego
Mesa, Jorge
Bruges, Ricardo
author_sort Vallejo Yepes, Camilo
collection PubMed
description Wilms' tumor is childhood’s most common renal tumor, and its presentation in the adult age is extremely rare. Due to the low frequency in adults, no standard management guidelines are available for this population, also the natural history of the disease and management is unclear. We present a case report of a 31-year-old woman with metastatic Wilms' tumor, with lymph node, lung and liver involvement; systemic treatment with chemotherapy was started, with complete clinical response. Finally, a literature review is performed to showcase the differences in the clinical course, prognosis, and treatment alternatives, in adult disease compared to childhood.
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spelling pubmed-82656922021-07-14 Adult Wilms' Tumor: Case Report and Literature Review Vallejo Yepes, Camilo Bermudez, Marcela Camacho-Nieto, Diego Mesa, Jorge Bruges, Ricardo Cureus Pathology Wilms' tumor is childhood’s most common renal tumor, and its presentation in the adult age is extremely rare. Due to the low frequency in adults, no standard management guidelines are available for this population, also the natural history of the disease and management is unclear. We present a case report of a 31-year-old woman with metastatic Wilms' tumor, with lymph node, lung and liver involvement; systemic treatment with chemotherapy was started, with complete clinical response. Finally, a literature review is performed to showcase the differences in the clinical course, prognosis, and treatment alternatives, in adult disease compared to childhood. Cureus 2021-06-08 /pmc/articles/PMC8265692/ /pubmed/34268047 http://dx.doi.org/10.7759/cureus.15524 Text en Copyright © 2021, Vallejo Yepes et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Vallejo Yepes, Camilo
Bermudez, Marcela
Camacho-Nieto, Diego
Mesa, Jorge
Bruges, Ricardo
Adult Wilms' Tumor: Case Report and Literature Review
title Adult Wilms' Tumor: Case Report and Literature Review
title_full Adult Wilms' Tumor: Case Report and Literature Review
title_fullStr Adult Wilms' Tumor: Case Report and Literature Review
title_full_unstemmed Adult Wilms' Tumor: Case Report and Literature Review
title_short Adult Wilms' Tumor: Case Report and Literature Review
title_sort adult wilms' tumor: case report and literature review
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265692/
https://www.ncbi.nlm.nih.gov/pubmed/34268047
http://dx.doi.org/10.7759/cureus.15524
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