Stability of a high-concentration monoclonal antibody solution produced by liquid–liquid phase separation

Subcutaneous injection of a low volume (<2 mL) high concentration (>100 mg/mL) formulation is an attractive administration strategy for monoclonal antibodies (mAbs) and other biopharmaceutical proteins. Using concentrated solutions may also be beneficial at various stages of bioprocessing. How...

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Detalles Bibliográficos
Autores principales: Bramham, Jack E., Davies, Stephanie A., Podmore, Adrian, Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265796/
https://www.ncbi.nlm.nih.gov/pubmed/34225583
http://dx.doi.org/10.1080/19420862.2021.1940666

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