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PI3K Inhibition by BKM120 Results in Antiproliferative Effects on Corticotroph Tumor Cells

Purpose: Cushing’s disease is associated with significant morbidity, thus additional tumor-directed drugs with the potential to exert antineoplastic effects on corticotroph adenoma cells are desired. The PI3K (phosphoinositide-3-kinase)/AKT (protein kinase B) pathway, which plays regulatory roles in...

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Detalles Bibliográficos
Autores principales:	Oliveira, Helen A, Bueno, Ana C, Pugliesi, Renata S, Silva-Júnior, Rui M P, de Castro, Margaret, Martins, Clarissa S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Neuroendocrinology and Pituitary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265828/ http://dx.doi.org/10.1210/jendso/bvab048.1116

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