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Genetic Predisposition to Numerous Large Ulcerating Basal Cell Carcinomas and Response to Immune Therapy

OBJECTIVE: Well-defined germ-line mutations in the PTCH1 gene are associated with syndromic multiple basal cell carcinomas (BCCs). Here, we used whole exome sequencing (WES) to identify the role of patched-1 in patients with multiple, unusually large BCCs. METHODS: A 72-year old patient presenting w...

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Detalles Bibliográficos
Autores principales:	Dasgeb, Bahar, Leila, Youssefian, Saeidian, Amir Hossein, Kang, Jun, Shi, Wenyin, Shoenberg, Elizabeth, Ertel, Adam, Fortina, Paolo, Vahidnezhad, Hassan, Uitto, Jouni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265835/ https://www.ncbi.nlm.nih.gov/pubmed/34278326 http://dx.doi.org/10.1097/JD9.0000000000000170

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