Modulation of Calcium Signaling by Chemogenetic Tools to Elucidate the Pathogenesis of Primary Aldosteronism

Primary aldosteronism (PA) is the most frequent form of secondary arterial hypertension. The identification of germline or somatic mutations in different genes coding for ion channels (KCNJ5, CACNA1D, CACNA1H and CLCN2) and ATPases (ATP1A1 and ATP2B3) defines PA as a channelopathy. These mutations p...

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Detalles Bibliográficos
Autores principales: Cosentino, Teresa, Fedlaoui, Bakhta, Giscos-Douriez, Isabelle, Fernandes-Rosa, Fabio Luiz, Magnus, Christopher, Sternson, Scott M, Zennaro, Maria-Christina, Boulkroun, Sheerazed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Cardiovascular Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265839/
http://dx.doi.org/10.1210/jendso/bvab048.599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265839/
http://dx.doi.org/10.1210/jendso/bvab048.599

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