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Modulation of Calcium Signaling by Chemogenetic Tools to Elucidate the Pathogenesis of Primary Aldosteronism
Primary aldosteronism (PA) is the most frequent form of secondary arterial hypertension. The identification of germline or somatic mutations in different genes coding for ion channels (KCNJ5, CACNA1D, CACNA1H and CLCN2) and ATPases (ATP1A1 and ATP2B3) defines PA as a channelopathy. These mutations p...
Autores principales: | Cosentino, Teresa, Fedlaoui, Bakhta, Giscos-Douriez, Isabelle, Fernandes-Rosa, Fabio Luiz, Magnus, Christopher, Sternson, Scott M, Zennaro, Maria-Christina, Boulkroun, Sheerazed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265839/ http://dx.doi.org/10.1210/jendso/bvab048.599 |
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