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Perirectal Extragastrointestinal Stromal Tumor: An Unusual Presentation
Gastrointestinal stromal tumors (GISTs), even though rare, remain the most common mesenchymal tumors of the gastrointestinal (GI) tract. When GISTs occur outside of the GI tract, they are termed extragastrointestinal stromal tumors (EGISTs). Most GISTs arise from the stomach (50-70%) and small intes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265861/ https://www.ncbi.nlm.nih.gov/pubmed/34268049 http://dx.doi.org/10.7759/cureus.15529 |
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author | Elagami, Mohamed M Khalid, Alman Kumar, Vinod Singhal, Monisha Grossman, Matthew A |
author_facet | Elagami, Mohamed M Khalid, Alman Kumar, Vinod Singhal, Monisha Grossman, Matthew A |
author_sort | Elagami, Mohamed M |
collection | PubMed |
description | Gastrointestinal stromal tumors (GISTs), even though rare, remain the most common mesenchymal tumors of the gastrointestinal (GI) tract. When GISTs occur outside of the GI tract, they are termed extragastrointestinal stromal tumors (EGISTs). Most GISTs arise from the stomach (50-70%) and small intestine (20-30%). A smaller percentage of these tumors also occurs in the large intestine (5%) and esophagus (2-5%). EGISTs have histopathological and molecular characteristics that are similar to GISTs. However, the precise incidence and tumor behavior of EGISTs are not fully understood. EGISTs have no specific symptoms or radiologic features, and in most cases, the presenting complaint is abdominal pain or discomfort. Yet, they tend to be more aggressive and have a worse prognosis than GISTs. Morphologic diagnosis based on microscopic examination of histological sections is the standard diagnostic procedure for GIST/EGIST. In this patient-centered study, we present a case of EGIST that originated in the anterior perirectal space, an extremely rare location; we also describe the endoscopic approach that was used to biopsy the tumor. |
format | Online Article Text |
id | pubmed-8265861 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-82658612021-07-14 Perirectal Extragastrointestinal Stromal Tumor: An Unusual Presentation Elagami, Mohamed M Khalid, Alman Kumar, Vinod Singhal, Monisha Grossman, Matthew A Cureus Internal Medicine Gastrointestinal stromal tumors (GISTs), even though rare, remain the most common mesenchymal tumors of the gastrointestinal (GI) tract. When GISTs occur outside of the GI tract, they are termed extragastrointestinal stromal tumors (EGISTs). Most GISTs arise from the stomach (50-70%) and small intestine (20-30%). A smaller percentage of these tumors also occurs in the large intestine (5%) and esophagus (2-5%). EGISTs have histopathological and molecular characteristics that are similar to GISTs. However, the precise incidence and tumor behavior of EGISTs are not fully understood. EGISTs have no specific symptoms or radiologic features, and in most cases, the presenting complaint is abdominal pain or discomfort. Yet, they tend to be more aggressive and have a worse prognosis than GISTs. Morphologic diagnosis based on microscopic examination of histological sections is the standard diagnostic procedure for GIST/EGIST. In this patient-centered study, we present a case of EGIST that originated in the anterior perirectal space, an extremely rare location; we also describe the endoscopic approach that was used to biopsy the tumor. Cureus 2021-06-08 /pmc/articles/PMC8265861/ /pubmed/34268049 http://dx.doi.org/10.7759/cureus.15529 Text en Copyright © 2021, Elagami et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Elagami, Mohamed M Khalid, Alman Kumar, Vinod Singhal, Monisha Grossman, Matthew A Perirectal Extragastrointestinal Stromal Tumor: An Unusual Presentation |
title | Perirectal Extragastrointestinal Stromal Tumor: An Unusual Presentation |
title_full | Perirectal Extragastrointestinal Stromal Tumor: An Unusual Presentation |
title_fullStr | Perirectal Extragastrointestinal Stromal Tumor: An Unusual Presentation |
title_full_unstemmed | Perirectal Extragastrointestinal Stromal Tumor: An Unusual Presentation |
title_short | Perirectal Extragastrointestinal Stromal Tumor: An Unusual Presentation |
title_sort | perirectal extragastrointestinal stromal tumor: an unusual presentation |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265861/ https://www.ncbi.nlm.nih.gov/pubmed/34268049 http://dx.doi.org/10.7759/cureus.15529 |
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