Cargando…

Long non-coding RNA HCP5 functions as a sponge of miR-29b-3p and promotes cell growth and metastasis in hepatocellular carcinoma through upregulating DNMT3A

Multiple studies have revealed that long non-coding RNA (lncRNAs) served as regulatory factors in modulating tumorigenesis of hepatocellular carcinoma (HCC). In the present study, we demonstrated that lncRNA HCP5 was overexpressed in HCC tissues and cell lines, and these findings were obvious even i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Yongping, Li, Kuan, Dai, Tu, Wang, Hong, Hua, Zhiyuan, Bian, Wuyang, Wang, Hao, Chen, Fangming, Ai, Xiaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266334/ https://www.ncbi.nlm.nih.gov/pubmed/34148029 http://dx.doi.org/10.18632/aging.203155

Ejemplares similares

LncRNA DHRS4-AS1 ameliorates hepatocellular carcinoma by suppressing proliferation and promoting apoptosis via miR-522-3p/SOCS5 axis
por: Zhou, Yongping, et al.
Publicado: (2021)

LncRNA HCP5 Promotes Cell Invasion and Migration by Sponging miR-29b-3p in Human Bladder Cancer
por: Zhao, Cheng, et al.
Publicado: (2020)

circ0093740 Promotes Tumor Growth and Metastasis by Sponging miR-136/145 and Upregulating DNMT3A in Wilms Tumor
por: Cao, Juan, et al.
Publicado: (2021)

circIQCH sponges miR-145 to promote breast cancer progression by upregulating DNMT3A expression
por: Li, Yuehua, et al.
Publicado: (2020)

Suppressing microRNA-29c promotes biliary atresia-related fibrosis by targeting DNMT3A and DNMT3B
por: Wang, Jian-yao, et al.
Publicado: (2019)

Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the β-catenin pathway
por: Zhou, Yongping, et al.
Publicado: (2020)

LncRNA HCP5 promotes follicular thyroid carcinoma progression via miRNAs sponge
por: Liang, Leilei, et al.
Publicado: (2018)

Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
por: Van Emburgh, Beth O., et al.
Publicado: (2011)

HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression
por: Liu, Yan, et al.
Publicado: (2021)

DNMT3A and DNMT3B in Breast Tumorigenesis and Potential Therapy
por: Man, Xiaxia, et al.
Publicado: (2022)

Correction: LncRNA HCP5A promotes follicular thyroid carcinoma progression via miRNAs sponge
por: Liang, Leilei, et al.
Publicado: (2019)

Expression of DNMT1 and DNMT3a Are Regulated by GLI1 in Human Pancreatic Cancer
por: He, ShanShan, et al.
Publicado: (2011)

Long Noncoding RNA HCP5 Regulates Pancreatic Cancer Gemcitabine (GEM) Resistance By Sponging Hsa-miR-214-3p To Target HDGF
por: Liu, Yunfei, et al.
Publicado: (2019)

FOXC1 promotes HCC proliferation and metastasis by Upregulating DNMT3B to induce DNA Hypermethylation of CTH promoter
por: Lin, Zhuoying, et al.
Publicado: (2021)

Long non-coding RNA H19 regulates E2F1 expression by competitively sponging endogenous miR-29a-3p in clear cell renal cell carcinoma
por: He, Haowei, et al.
Publicado: (2017)

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
por: Liao, Jing, et al.
Publicado: (2015)

Oncogenic Roles and Inhibitors of DNMT1, DNMT3A, and DNMT3B in Acute Myeloid Leukaemia
por: Wong, Kah Keng, et al.
Publicado: (2019)

Dnmt3aa but Not Dnmt3ab Is Required for Maintenance of Gametogenesis in Nile Tilapia (Oreochromis niloticus)
por: Wang, Feilong, et al.
Publicado: (2021)

MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice
por: Yang, Ya-Ling, et al.
Publicado: (2019)

HCP5 is a SMAD3-responsive long non-coding RNA that promotes lung adenocarcinoma metastasis via miR-203/SNAI axis
por: Jiang, Lin, et al.
Publicado: (2019)

DNMT1, DNMT3A and DNMT3B Polymorphisms Associated With Gastric Cancer Risk: A Systematic Review and Meta-analysis
por: Li, Hongjia, et al.
Publicado: (2016)

LncRNA LINC00511 Acts as an Oncogene in Colorectal Cancer via Sponging miR-29c-3p to Upregulate NFIA
por: Hu, Yu, et al.
Publicado: (2021)

DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B In Vivo
por: Wienholz, Bethany L., et al.
Publicado: (2010)

Nucleation and growth mechanisms of hcp domains in compressed iron
por: Pang, Wei-Wei, et al.
Publicado: (2014)

DNMT1, DNMT3A and DNMT3B gene variants in relation to ovarian cancer risk in the Polish population
por: Mostowska, Adrianna, et al.
Publicado: (2013)

Long noncoding RNA HCP5 suppresses skin cutaneous melanoma development by regulating RARRES3 gene expression via sponging miR-12
por: Wei, Xihua, et al.
Publicado: (2019)

The acute myeloid leukemia variant DNMT3A Arg882His is a DNMT3B-like enzyme
por: Norvil, Allison B, et al.
Publicado: (2020)

Downregulation of miR-29b targets DNMT3b to suppress cellular apoptosis and enhance proliferation in pancreatic cancer
por: Wang, Li-Hua, et al.
Publicado: (2018)

Long noncoding RNA TUG1 upregulates VEGFA to enhance malignant behaviors in stomach adenocarcinoma by sponging miR‐29c‐3p
por: Jin, Yanzhao, et al.
Publicado: (2021)

Genetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans
por: Hajeri, Vinita A, et al.
Publicado: (2008)

Structure of DNA methyltransferases DNMT3A/DNMT3B bound to a nucleosome
por: Xu, Ting-Hai, et al.
Publicado: (2020)

DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma
por: Camero, Simona, et al.
Publicado: (2021)

Hemolysin Co-regulated Family Proteins Hcp1 and Hcp2 Contribute to Edwardsiella ictaluri Pathogenesis
por: Kalindamar, Safak, et al.
Publicado: (2021)

LncRNA HCP5 promotes triple negative breast cancer progression as a ceRNA to regulate BIRC3 by sponging miR‐219a‐5p
por: Wang, Lihong, et al.
Publicado: (2019)

Long Non-coding RNA TUG1 Modulates Expression of Elastin to Relieve Bronchopulmonary Dysplasia via Sponging miR-29a-3p
por: Zhong, Qinghua, et al.
Publicado: (2020)

The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation
por: Zeng, Yang, et al.
Publicado: (2020)

Downregulated miR-29a/b/c during Contact Inhibition Stage Promote 3T3-L1 Adipogenesis by Targeting DNMT3A
por: Zhu, Yingjie, et al.
Publicado: (2017)

microRNA-29a inhibits cardiac fibrosis in Sprague-Dawley rats by downregulating the expression of DNMT3A
por: Qin, Run-He, et al.
Publicado: (2018)

MCM3AP-AS1 KD Inhibits Proliferation, Invasion, and Migration of PCa Cells via DNMT1/DNMT3 (A/B) Methylation-Mediated Upregulation of NPY1R
por: Li, Xin, et al.
Publicado: (2020)

MCM3AP-AS1 KD Inhibits Proliferation, Invasion, and Migration of PCa Cells via DNMT1/DNMT3 (A/B) Methylation-Mediated Upregulation of NPY1R
por: Li, Xin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7s9lfvsn3fpdubes515ejuomj2