Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway

Diabetic patients are more vulnerable to cerebral ischemia-reperfusion (CIR) injury and have a worse prognosis and higher mortality after ischemic stroke than non-diabetic counterparts. Melatonin can exert neuroprotective effects against CIR injury in nondiabetic animal models. However, its effects...

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Detalles Bibliográficos
Autores principales: Liu, Lian, Cao, Quan, Gao, Wenwei, Li, Bingyu, Xia, Zhongyuan, Zhao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266371/
https://www.ncbi.nlm.nih.gov/pubmed/34118791
http://dx.doi.org/10.18632/aging.203137

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