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Differential responses of neurons, astrocytes, and microglia to G-quadruplex stabilization

The G-quadruplex (G4-DNA or G4) is a secondary DNA structure formed by DNA sequences containing multiple runs of guanines. While it is now firmly established that stabilized G4s lead to enhanced genomic instability in cancer cells, whether and how G4s contribute to genomic instability in brain cells...

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Detalles Bibliográficos
Autores principales: Tabor, Natalie, Ngwa, Conelius, Mitteaux, Jeremie, Meyer, Matthew D., Moruno-Manchon, Jose F., Zhu, Liang, Liu, Fudong, Monchaud, David, McCullough, Louise D., Tsvetkov, Andrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266374/
https://www.ncbi.nlm.nih.gov/pubmed/34139671
http://dx.doi.org/10.18632/aging.203222

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