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Homozygous Co-Deletion of Type I Interferons and CDKN2A Genes in Thoracic Cancers: Potential Consequences for Therapy

Homozygous deletion (HD) of the tumor suppressor gene CDKN2A is the most frequent genetic alteration in malignant pleural mesothelioma and is also frequent in non-small cell lung cancers. This HD is often accompanied by the HD of the type I interferons (IFN I) genes that are located closed to the CD...

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Detalles Bibliográficos
Autores principales:	Grard, Marion, Chatelain, Camille, Delaunay, Tiphaine, Pons-Tostivint, Elvire, Bennouna, Jaafar, Fonteneau, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266377/ https://www.ncbi.nlm.nih.gov/pubmed/34249754 http://dx.doi.org/10.3389/fonc.2021.695770

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