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Standardizing characterization of membrane active peptides with microfluidics
Antimicrobial peptides (AMPs) are emerging as important players in the fight against antibiotic resistance. In parallel, the field of microfluidics has matured and its benefits are being exploited in applications of biomimetics and standardized testing. Membrane models are essential tools extensivel...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266397/ https://www.ncbi.nlm.nih.gov/pubmed/34257793 http://dx.doi.org/10.1063/5.0048906 |
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author | Al Nahas, Kareem Keyser, Ulrich F. |
author_facet | Al Nahas, Kareem Keyser, Ulrich F. |
author_sort | Al Nahas, Kareem |
collection | PubMed |
description | Antimicrobial peptides (AMPs) are emerging as important players in the fight against antibiotic resistance. In parallel, the field of microfluidics has matured and its benefits are being exploited in applications of biomimetics and standardized testing. Membrane models are essential tools extensively utilized in studying the activity and modes of action of AMPs. Here, we describe how the utilization of microfluidic platforms in characterizing membrane active peptides can develop a reliable colorful image that classical techniques have rendered black and white. |
format | Online Article Text |
id | pubmed-8266397 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | AIP Publishing LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-82663972021-07-12 Standardizing characterization of membrane active peptides with microfluidics Al Nahas, Kareem Keyser, Ulrich F. Biomicrofluidics Perspectives Antimicrobial peptides (AMPs) are emerging as important players in the fight against antibiotic resistance. In parallel, the field of microfluidics has matured and its benefits are being exploited in applications of biomimetics and standardized testing. Membrane models are essential tools extensively utilized in studying the activity and modes of action of AMPs. Here, we describe how the utilization of microfluidic platforms in characterizing membrane active peptides can develop a reliable colorful image that classical techniques have rendered black and white. AIP Publishing LLC 2021-07-07 /pmc/articles/PMC8266397/ /pubmed/34257793 http://dx.doi.org/10.1063/5.0048906 Text en © 2021 Author(s). https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Perspectives Al Nahas, Kareem Keyser, Ulrich F. Standardizing characterization of membrane active peptides with microfluidics |
title | Standardizing characterization of membrane active peptides with microfluidics |
title_full | Standardizing characterization of membrane active peptides with microfluidics |
title_fullStr | Standardizing characterization of membrane active peptides with microfluidics |
title_full_unstemmed | Standardizing characterization of membrane active peptides with microfluidics |
title_short | Standardizing characterization of membrane active peptides with microfluidics |
title_sort | standardizing characterization of membrane active peptides with microfluidics |
topic | Perspectives |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266397/ https://www.ncbi.nlm.nih.gov/pubmed/34257793 http://dx.doi.org/10.1063/5.0048906 |
work_keys_str_mv | AT alnahaskareem standardizingcharacterizationofmembraneactivepeptideswithmicrofluidics AT keyserulrichf standardizingcharacterizationofmembraneactivepeptideswithmicrofluidics |