Human tRNAs with inosine 34 are essential to efficiently translate eukarya-specific low-complexity proteins

The modification of adenosine to inosine at the wobble position (I34) of tRNA anticodons is an abundant and essential feature of eukaryotic tRNAs. The expansion of inosine-containing tRNAs in eukaryotes followed the transformation of the homodimeric bacterial enzyme TadA, which generates I34 in tRNA...

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Detalles Bibliográficos
Autores principales: Torres, Adrian Gabriel, Rodríguez-Escribà, Marta, Marcet-Houben, Marina, Santos Vieira, Helaine Graziele, Camacho, Noelia, Catena, Helena, Murillo Recio, Marina, Rafels-Ybern, Àlbert, Reina, Oscar, Torres, Francisco Miguel, Pardo-Saganta, Ana, Gabaldón, Toni, Novoa, Eva Maria, Ribas de Pouplana, Lluís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266599/
https://www.ncbi.nlm.nih.gov/pubmed/34125917
http://dx.doi.org/10.1093/nar/gkab461

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