A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States

Macrolide resistance was found in 39.5% of 3626 nonduplicate Streptococcus pneumoniae isolates from adult ambulatory and inpatient settings at 329 US hospitals (2018–2019). Macrolide resistance was significantly higher for respiratory vs blood isolates and ambulatory vs inpatient settings. Despite g...

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Autores principales: Gupta, Vikas, Yu, Kalvin C, Schranz, Jennifer, Gelone, Steven P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266646/
https://www.ncbi.nlm.nih.gov/pubmed/34250183
http://dx.doi.org/10.1093/ofid/ofab063
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author Gupta, Vikas
Yu, Kalvin C
Schranz, Jennifer
Gelone, Steven P
author_facet Gupta, Vikas
Yu, Kalvin C
Schranz, Jennifer
Gelone, Steven P
author_sort Gupta, Vikas
collection PubMed
description Macrolide resistance was found in 39.5% of 3626 nonduplicate Streptococcus pneumoniae isolates from adult ambulatory and inpatient settings at 329 US hospitals (2018–2019). Macrolide resistance was significantly higher for respiratory vs blood isolates and ambulatory vs inpatient settings. Despite geographic variation, S. pneumoniae macrolide resistance was >25% in most regions.
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spelling pubmed-82666462021-07-09 A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States Gupta, Vikas Yu, Kalvin C Schranz, Jennifer Gelone, Steven P Open Forum Infect Dis Brief Reports Macrolide resistance was found in 39.5% of 3626 nonduplicate Streptococcus pneumoniae isolates from adult ambulatory and inpatient settings at 329 US hospitals (2018–2019). Macrolide resistance was significantly higher for respiratory vs blood isolates and ambulatory vs inpatient settings. Despite geographic variation, S. pneumoniae macrolide resistance was >25% in most regions. Oxford University Press 2021-02-04 /pmc/articles/PMC8266646/ /pubmed/34250183 http://dx.doi.org/10.1093/ofid/ofab063 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Gupta, Vikas
Yu, Kalvin C
Schranz, Jennifer
Gelone, Steven P
A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States
title A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States
title_full A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States
title_fullStr A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States
title_full_unstemmed A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States
title_short A Multicenter Evaluation of the US Prevalence and Regional Variation in Macrolide-Resistant S. pneumoniae in Ambulatory and Hospitalized Adult Patients in the United States
title_sort multicenter evaluation of the us prevalence and regional variation in macrolide-resistant s. pneumoniae in ambulatory and hospitalized adult patients in the united states
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266646/
https://www.ncbi.nlm.nih.gov/pubmed/34250183
http://dx.doi.org/10.1093/ofid/ofab063
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