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Formation of frameshift-stimulating RNA pseudoknots is facilitated by remodeling of their folding intermediates
Programmed –1 ribosomal frameshifting is an essential regulation mechanism of translation in viruses and bacteria. It is stimulated by mRNA structures inside the coding region. As the structure is unfolded repeatedly by consecutive translating ribosomes, whether it can refold properly each time is i...
Autores principales: | Hsu, Chiung-Fang, Chang, Kai-Chun, Chen, Yi-Lan, Hsieh, Po-Szu, Lee, An-I, Tu, Jui-Yun, Chen, Yu-Ting, Wen, Jin-Der |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266650/ https://www.ncbi.nlm.nih.gov/pubmed/34161580 http://dx.doi.org/10.1093/nar/gkab512 |
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