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Single-round deoxyribozyme discovery
Artificial evolution experiments typically use libraries of ∼10(15) sequences and require multiple rounds of selection to identify rare variants with a desired activity. Based on the simple structures of some aptamers and nucleic acid enzymes, we hypothesized that functional motifs could be isolated...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266665/ https://www.ncbi.nlm.nih.gov/pubmed/34133739 http://dx.doi.org/10.1093/nar/gkab504 |