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Effect of Various Dosing Conditions on the Pharmacokinetics of Oral Semaglutide, a Human Glucagon-Like Peptide-1 Analogue in a Tablet Formulation

INTRODUCTION: Oral semaglutide is a novel tablet formulation of the human glucagon-like peptide-1 analogue semaglutide. In two trials, the effects of prior food ingestion (food effect), post-dose fasting period and water volume with dosing (dosing conditions) on oral semaglutide pharmacokinetics wer...

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Detalles Bibliográficos
Autores principales: Bækdal, Tine A., Breitschaft, Astrid, Donsmark, Morten, Maarbjerg, Stine J., Søndergaard, Flemming L., Borregaard, Jeanett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266944/
https://www.ncbi.nlm.nih.gov/pubmed/34080123
http://dx.doi.org/10.1007/s13300-021-01078-y