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Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected

BACKGROUND: An alarming cerebro/cardiovascular collateral damage, reflected by a decline in admissions for acute stroke (AS) and acute coronary syndrome (ACS), was observed during the initial phase of the COVID-19 pandemic, thereby leading to a re-design of public campaigns. However, there are limit...

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Autores principales: Katsouras, Christos, Tsivgoulis, Georgios, Papafaklis, Michail, Karapanayiotides, Theodore, Alexopoulos, Dimitrios, Ntais, Evangelos, Papagiannopoulou, Georgia, Koutroulou, Ioanna, Ziakas, Antonios, Sianos, Georgios, Kouparanis, Antonios, Trivilou, Paraskevi, Ballas, Christos, Samara, Ioanna, Kosmidou, Maria, Palaiodimou, Lina, Grigoriadis, Nikolaos, Michalis, Lampros K., Giannopoulos, Sotirios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267023/
https://www.ncbi.nlm.nih.gov/pubmed/34285718
http://dx.doi.org/10.1177/17562864211029540
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author Katsouras, Christos
Tsivgoulis, Georgios
Papafaklis, Michail
Karapanayiotides, Theodore
Alexopoulos, Dimitrios
Ntais, Evangelos
Papagiannopoulou, Georgia
Koutroulou, Ioanna
Ziakas, Antonios
Sianos, Georgios
Kouparanis, Antonios
Trivilou, Paraskevi
Ballas, Christos
Samara, Ioanna
Kosmidou, Maria
Palaiodimou, Lina
Grigoriadis, Nikolaos
Michalis, Lampros K.
Giannopoulos, Sotirios
author_facet Katsouras, Christos
Tsivgoulis, Georgios
Papafaklis, Michail
Karapanayiotides, Theodore
Alexopoulos, Dimitrios
Ntais, Evangelos
Papagiannopoulou, Georgia
Koutroulou, Ioanna
Ziakas, Antonios
Sianos, Georgios
Kouparanis, Antonios
Trivilou, Paraskevi
Ballas, Christos
Samara, Ioanna
Kosmidou, Maria
Palaiodimou, Lina
Grigoriadis, Nikolaos
Michalis, Lampros K.
Giannopoulos, Sotirios
author_sort Katsouras, Christos
collection PubMed
description BACKGROUND: An alarming cerebro/cardiovascular collateral damage, reflected by a decline in admissions for acute stroke (AS) and acute coronary syndrome (ACS), was observed during the initial phase of the COVID-19 pandemic, thereby leading to a re-design of public campaigns. However, there are limited data regarding the AS and ACS hospitalization rates during the second wave of the pandemic, which was followed by re-imposition of lockdowns. METHODS: We calculated the rate of AS and ACS hospitalizations from three representative tertiary care hospitals in Greece during a 2-month period (November–December 2020) of the second wave of the COVID-19 pandemic compared with the corresponding control period in 2019 from three representative tertiary care hospitals in Greece. This was a follow-up study with identical design to our previous report evaluating AS and ACS hospitalizations during the first wave of the pandemic (March–April 2020). RESULTS: Compared with 2019, there was a 34% relative reduction of AS hospitalizations [incidence rate ratio (IRR): 0.66, 95% confidence interval (CI): 0.48–0.92, p = 0.013] and 33% relative reduction of ACS hospitalizations (IRR: 0.67, 95% CI: 0.54–0.83, p < 0.001) during the second wave of the COVID-19 pandemic. The relative reduction was smaller and did not reach the level of statistical significance for the respective syndromes (haemorrhagic stroke: IRR 0.87, 95% CI: 0.41–1.82, p = 0.71; ST-elevation myocardial infarction: IRR 0.81, 95% CI: 0.57–1.14, p = 0.22). CONCLUSION: AS and ACS hospitalizations were persistently reduced during the second wave of the COVID-19 pandemic compared with 2019 in Greece. This decline was similar to the observations during the first wave despite the large differences in the epidemiological COVID-19 burden. Lockdowns, a common characteristic in both waves, appear to have a detrimental indirect impact on cerebro/cardiovascular diseases in the general population.
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spelling pubmed-82670232021-07-19 Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected Katsouras, Christos Tsivgoulis, Georgios Papafaklis, Michail Karapanayiotides, Theodore Alexopoulos, Dimitrios Ntais, Evangelos Papagiannopoulou, Georgia Koutroulou, Ioanna Ziakas, Antonios Sianos, Georgios Kouparanis, Antonios Trivilou, Paraskevi Ballas, Christos Samara, Ioanna Kosmidou, Maria Palaiodimou, Lina Grigoriadis, Nikolaos Michalis, Lampros K. Giannopoulos, Sotirios Ther Adv Neurol Disord Original Research BACKGROUND: An alarming cerebro/cardiovascular collateral damage, reflected by a decline in admissions for acute stroke (AS) and acute coronary syndrome (ACS), was observed during the initial phase of the COVID-19 pandemic, thereby leading to a re-design of public campaigns. However, there are limited data regarding the AS and ACS hospitalization rates during the second wave of the pandemic, which was followed by re-imposition of lockdowns. METHODS: We calculated the rate of AS and ACS hospitalizations from three representative tertiary care hospitals in Greece during a 2-month period (November–December 2020) of the second wave of the COVID-19 pandemic compared with the corresponding control period in 2019 from three representative tertiary care hospitals in Greece. This was a follow-up study with identical design to our previous report evaluating AS and ACS hospitalizations during the first wave of the pandemic (March–April 2020). RESULTS: Compared with 2019, there was a 34% relative reduction of AS hospitalizations [incidence rate ratio (IRR): 0.66, 95% confidence interval (CI): 0.48–0.92, p = 0.013] and 33% relative reduction of ACS hospitalizations (IRR: 0.67, 95% CI: 0.54–0.83, p < 0.001) during the second wave of the COVID-19 pandemic. The relative reduction was smaller and did not reach the level of statistical significance for the respective syndromes (haemorrhagic stroke: IRR 0.87, 95% CI: 0.41–1.82, p = 0.71; ST-elevation myocardial infarction: IRR 0.81, 95% CI: 0.57–1.14, p = 0.22). CONCLUSION: AS and ACS hospitalizations were persistently reduced during the second wave of the COVID-19 pandemic compared with 2019 in Greece. This decline was similar to the observations during the first wave despite the large differences in the epidemiological COVID-19 burden. Lockdowns, a common characteristic in both waves, appear to have a detrimental indirect impact on cerebro/cardiovascular diseases in the general population. SAGE Publications 2021-07-07 /pmc/articles/PMC8267023/ /pubmed/34285718 http://dx.doi.org/10.1177/17562864211029540 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Katsouras, Christos
Tsivgoulis, Georgios
Papafaklis, Michail
Karapanayiotides, Theodore
Alexopoulos, Dimitrios
Ntais, Evangelos
Papagiannopoulou, Georgia
Koutroulou, Ioanna
Ziakas, Antonios
Sianos, Georgios
Kouparanis, Antonios
Trivilou, Paraskevi
Ballas, Christos
Samara, Ioanna
Kosmidou, Maria
Palaiodimou, Lina
Grigoriadis, Nikolaos
Michalis, Lampros K.
Giannopoulos, Sotirios
Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected
title Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected
title_full Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected
title_fullStr Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected
title_full_unstemmed Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected
title_short Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected
title_sort persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the covid-19 pandemic in greece: collateral damage unaffected
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267023/
https://www.ncbi.nlm.nih.gov/pubmed/34285718
http://dx.doi.org/10.1177/17562864211029540
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