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High-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study
OBJECTIVE: To evaluate the effect of high-dose prednisolone on the functional outcome of patients with early-stage primary frozen shoulder. METHODS: Eighteen patients treated with oral prednisolone at an initial dose of 1 mg/kg/day for primary frozen shoulder were retrospectively evaluated. The pati...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267043/ https://www.ncbi.nlm.nih.gov/pubmed/34229518 http://dx.doi.org/10.1177/03000605211024875 |
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author | Atici, Teoman Ermutlu, Cenk Akesen, Selcan Özyalçin, Ali |
author_facet | Atici, Teoman Ermutlu, Cenk Akesen, Selcan Özyalçin, Ali |
author_sort | Atici, Teoman |
collection | PubMed |
description | OBJECTIVE: To evaluate the effect of high-dose prednisolone on the functional outcome of patients with early-stage primary frozen shoulder. METHODS: Eighteen patients treated with oral prednisolone at an initial dose of 1 mg/kg/day for primary frozen shoulder were retrospectively evaluated. The patients’ range of motion, Disabilities of the Arm, Shoulder, and Hand (DASH) score, Constant–Murley score, American Shoulder and Elbow Surgeons (ASES) score, and visual analog scale score were recorded at baseline and at 4 weeks and 6 months after treatment. RESULTS: Rapid recovery of shoulder motion was noted at 4 weeks with the exception of abduction, which was maintained at 6 months. Significant improvement in pain perception and the Constant–Murley score was evident at 4 weeks and extended to 6 months. The DASH and ASES scores did not show significant improvement in the first 4 weeks but were significantly improved at 6 months. CONCLUSION: High-dose oral prednisolone treatment provides rapid symptom resolution that persists long after drug discontinuation. The early treatment period is characterized by marked reduction in pain and rapid recovery of shoulder motion. Improvements in functional outcomes and disability indices tend to be more subtle in the early period but significantly improve during late treatment. |
format | Online Article Text |
id | pubmed-8267043 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-82670432021-07-19 High-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study Atici, Teoman Ermutlu, Cenk Akesen, Selcan Özyalçin, Ali J Int Med Res Retrospective Clinical Research Report OBJECTIVE: To evaluate the effect of high-dose prednisolone on the functional outcome of patients with early-stage primary frozen shoulder. METHODS: Eighteen patients treated with oral prednisolone at an initial dose of 1 mg/kg/day for primary frozen shoulder were retrospectively evaluated. The patients’ range of motion, Disabilities of the Arm, Shoulder, and Hand (DASH) score, Constant–Murley score, American Shoulder and Elbow Surgeons (ASES) score, and visual analog scale score were recorded at baseline and at 4 weeks and 6 months after treatment. RESULTS: Rapid recovery of shoulder motion was noted at 4 weeks with the exception of abduction, which was maintained at 6 months. Significant improvement in pain perception and the Constant–Murley score was evident at 4 weeks and extended to 6 months. The DASH and ASES scores did not show significant improvement in the first 4 weeks but were significantly improved at 6 months. CONCLUSION: High-dose oral prednisolone treatment provides rapid symptom resolution that persists long after drug discontinuation. The early treatment period is characterized by marked reduction in pain and rapid recovery of shoulder motion. Improvements in functional outcomes and disability indices tend to be more subtle in the early period but significantly improve during late treatment. SAGE Publications 2021-07-06 /pmc/articles/PMC8267043/ /pubmed/34229518 http://dx.doi.org/10.1177/03000605211024875 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Retrospective Clinical Research Report Atici, Teoman Ermutlu, Cenk Akesen, Selcan Özyalçin, Ali High-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study |
title | High-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study |
title_full | High-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study |
title_fullStr | High-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study |
title_full_unstemmed | High-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study |
title_short | High-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study |
title_sort | high-dose short-course oral corticosteroid protocol for treatment of primary frozen shoulder: a retrospective cohort study |
topic | Retrospective Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267043/ https://www.ncbi.nlm.nih.gov/pubmed/34229518 http://dx.doi.org/10.1177/03000605211024875 |
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