Cargando…

The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study

BACKGROUND: Thyroid cancer is a growing threat to human health. Few studies have explored trends of thyroid cancer and relationships with social development factors. In this study, we explored the trend and relationship based on GBD. METHODS: By using GBD study, we obtained detailed data of thyroid...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhai, Mimi, Zhang, Dan, Long, Jianhai, Gong, Yi, Ye, Fei, Liu, Sushun, Li, Yamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267141/
https://www.ncbi.nlm.nih.gov/pubmed/34002931
http://dx.doi.org/10.1002/cam4.3970
_version_ 1783720082330877952
author Zhai, Mimi
Zhang, Dan
Long, Jianhai
Gong, Yi
Ye, Fei
Liu, Sushun
Li, Yamin
author_facet Zhai, Mimi
Zhang, Dan
Long, Jianhai
Gong, Yi
Ye, Fei
Liu, Sushun
Li, Yamin
author_sort Zhai, Mimi
collection PubMed
description BACKGROUND: Thyroid cancer is a growing threat to human health. Few studies have explored trends of thyroid cancer and relationships with social development factors. In this study, we explored the trend and relationship based on GBD. METHODS: By using GBD study, we obtained detailed data of thyroid cancer. Incidence, mortality and DALY were used to assess epidemiological characteristics. ASR and EAPC were used to estimate the trend. RESULTS: Globally, the incidence significantly increased from 1990 to 2017, especially in high‐income regions. Males and middle SDI region demonstrated a higher increase of age‐standardized incidence rates. Unlike incidence trend, mortality trend showed a minor increase, and even showed a decreasing trend in some regions such as Eastern Sub‐Saharan Africa. Additionally, the DALY trend also demonstrated a slightly increase with an EAPC of 0.77 (95% CI 0.73–0.81). More significant increase of DALY was found in males, middle SDI region and high‐income Asia Pacific. The incidence of thyroid cancer peaked in middle‐aged people, while the mortality and DALY peaked in elder‐aged. Moreover, the proportion of thyroid cancer deaths contributable to high BMI was highest in developed countries and middle‐aged people. CONCLUSIONS: Thyroid cancer is a public health problem worldwide. Over‐diagnosis might be partly responsible for its rising trend. It remains us to revise the guidelines to avoid unnecessary burdens. Moreover, we should pay attention to the risk factors of thyroid cancer. More targeted measures should be formulated to improve potential environmental and lifestyle‐related factors which might contribute to rising trend of thyroid cancer.
format Online
Article
Text
id pubmed-8267141
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-82671412021-07-13 The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study Zhai, Mimi Zhang, Dan Long, Jianhai Gong, Yi Ye, Fei Liu, Sushun Li, Yamin Cancer Med Cancer Prevention BACKGROUND: Thyroid cancer is a growing threat to human health. Few studies have explored trends of thyroid cancer and relationships with social development factors. In this study, we explored the trend and relationship based on GBD. METHODS: By using GBD study, we obtained detailed data of thyroid cancer. Incidence, mortality and DALY were used to assess epidemiological characteristics. ASR and EAPC were used to estimate the trend. RESULTS: Globally, the incidence significantly increased from 1990 to 2017, especially in high‐income regions. Males and middle SDI region demonstrated a higher increase of age‐standardized incidence rates. Unlike incidence trend, mortality trend showed a minor increase, and even showed a decreasing trend in some regions such as Eastern Sub‐Saharan Africa. Additionally, the DALY trend also demonstrated a slightly increase with an EAPC of 0.77 (95% CI 0.73–0.81). More significant increase of DALY was found in males, middle SDI region and high‐income Asia Pacific. The incidence of thyroid cancer peaked in middle‐aged people, while the mortality and DALY peaked in elder‐aged. Moreover, the proportion of thyroid cancer deaths contributable to high BMI was highest in developed countries and middle‐aged people. CONCLUSIONS: Thyroid cancer is a public health problem worldwide. Over‐diagnosis might be partly responsible for its rising trend. It remains us to revise the guidelines to avoid unnecessary burdens. Moreover, we should pay attention to the risk factors of thyroid cancer. More targeted measures should be formulated to improve potential environmental and lifestyle‐related factors which might contribute to rising trend of thyroid cancer. John Wiley and Sons Inc. 2021-05-18 /pmc/articles/PMC8267141/ /pubmed/34002931 http://dx.doi.org/10.1002/cam4.3970 Text en © 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cancer Prevention
Zhai, Mimi
Zhang, Dan
Long, Jianhai
Gong, Yi
Ye, Fei
Liu, Sushun
Li, Yamin
The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study
title The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study
title_full The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study
title_fullStr The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study
title_full_unstemmed The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study
title_short The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study
title_sort global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: a systematic analysis for the global burden of disease study
topic Cancer Prevention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267141/
https://www.ncbi.nlm.nih.gov/pubmed/34002931
http://dx.doi.org/10.1002/cam4.3970
work_keys_str_mv AT zhaimimi theglobalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT zhangdan theglobalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT longjianhai theglobalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT gongyi theglobalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT yefei theglobalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT liusushun theglobalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT liyamin theglobalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT zhaimimi globalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT zhangdan globalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT longjianhai globalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT gongyi globalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT yefei globalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT liusushun globalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy
AT liyamin globalburdenofthyroidcanceranditsattributableriskfactorin195countriesandterritoriesasystematicanalysisfortheglobalburdenofdiseasestudy