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A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances

Cerebellar malfunctions significantly impact the regulation of the sleep–wakefulness transition. The possible mechanism for this effect is still unknown. Evidence on the role of cerebellar processing in the sleep–wake cycle is derived mainly from animal studies, and clinical management of the sleep–...

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Detalles Bibliográficos
Autores principales: Song, Bijia, Zhu, Jun-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267147/
https://www.ncbi.nlm.nih.gov/pubmed/34248474
http://dx.doi.org/10.3389/fnins.2021.590619
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author Song, Bijia
Zhu, Jun-Chao
author_facet Song, Bijia
Zhu, Jun-Chao
author_sort Song, Bijia
collection PubMed
description Cerebellar malfunctions significantly impact the regulation of the sleep–wakefulness transition. The possible mechanism for this effect is still unknown. Evidence on the role of cerebellar processing in the sleep–wake cycle is derived mainly from animal studies, and clinical management of the sleep–wake cycle is also challenging. The purpose of this review is to investigate the role of cerebellar activity during normal sleep and the association between cerebellar dysfunction and sleep disorders. Large-scale, multicenter trials are still needed to confirm these findings and provide early identification and intervention strategies to improve cerebellar function and the sleep quality of patients.
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spelling pubmed-82671472021-07-10 A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances Song, Bijia Zhu, Jun-Chao Front Neurosci Neuroscience Cerebellar malfunctions significantly impact the regulation of the sleep–wakefulness transition. The possible mechanism for this effect is still unknown. Evidence on the role of cerebellar processing in the sleep–wake cycle is derived mainly from animal studies, and clinical management of the sleep–wake cycle is also challenging. The purpose of this review is to investigate the role of cerebellar activity during normal sleep and the association between cerebellar dysfunction and sleep disorders. Large-scale, multicenter trials are still needed to confirm these findings and provide early identification and intervention strategies to improve cerebellar function and the sleep quality of patients. Frontiers Media S.A. 2021-06-25 /pmc/articles/PMC8267147/ /pubmed/34248474 http://dx.doi.org/10.3389/fnins.2021.590619 Text en Copyright © 2021 Song and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Song, Bijia
Zhu, Jun-Chao
A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances
title A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances
title_full A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances
title_fullStr A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances
title_full_unstemmed A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances
title_short A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances
title_sort narrative review of cerebellar malfunctions and sleep disturbances
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267147/
https://www.ncbi.nlm.nih.gov/pubmed/34248474
http://dx.doi.org/10.3389/fnins.2021.590619
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