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A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances
Cerebellar malfunctions significantly impact the regulation of the sleep–wakefulness transition. The possible mechanism for this effect is still unknown. Evidence on the role of cerebellar processing in the sleep–wake cycle is derived mainly from animal studies, and clinical management of the sleep–...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267147/ https://www.ncbi.nlm.nih.gov/pubmed/34248474 http://dx.doi.org/10.3389/fnins.2021.590619 |
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author | Song, Bijia Zhu, Jun-Chao |
author_facet | Song, Bijia Zhu, Jun-Chao |
author_sort | Song, Bijia |
collection | PubMed |
description | Cerebellar malfunctions significantly impact the regulation of the sleep–wakefulness transition. The possible mechanism for this effect is still unknown. Evidence on the role of cerebellar processing in the sleep–wake cycle is derived mainly from animal studies, and clinical management of the sleep–wake cycle is also challenging. The purpose of this review is to investigate the role of cerebellar activity during normal sleep and the association between cerebellar dysfunction and sleep disorders. Large-scale, multicenter trials are still needed to confirm these findings and provide early identification and intervention strategies to improve cerebellar function and the sleep quality of patients. |
format | Online Article Text |
id | pubmed-8267147 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82671472021-07-10 A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances Song, Bijia Zhu, Jun-Chao Front Neurosci Neuroscience Cerebellar malfunctions significantly impact the regulation of the sleep–wakefulness transition. The possible mechanism for this effect is still unknown. Evidence on the role of cerebellar processing in the sleep–wake cycle is derived mainly from animal studies, and clinical management of the sleep–wake cycle is also challenging. The purpose of this review is to investigate the role of cerebellar activity during normal sleep and the association between cerebellar dysfunction and sleep disorders. Large-scale, multicenter trials are still needed to confirm these findings and provide early identification and intervention strategies to improve cerebellar function and the sleep quality of patients. Frontiers Media S.A. 2021-06-25 /pmc/articles/PMC8267147/ /pubmed/34248474 http://dx.doi.org/10.3389/fnins.2021.590619 Text en Copyright © 2021 Song and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Song, Bijia Zhu, Jun-Chao A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances |
title | A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances |
title_full | A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances |
title_fullStr | A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances |
title_full_unstemmed | A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances |
title_short | A Narrative Review of Cerebellar Malfunctions and Sleep Disturbances |
title_sort | narrative review of cerebellar malfunctions and sleep disturbances |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267147/ https://www.ncbi.nlm.nih.gov/pubmed/34248474 http://dx.doi.org/10.3389/fnins.2021.590619 |
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