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High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity

Cytotoxic T lymphocytes (CTLs) are key players to eliminate tumorigenic or pathogen-infected cells using lytic granules (LG) and Fas ligand (FasL) pathways. Depletion of glucose leads to severely impaired cytotoxic function of CTLs. However, the impact of excessive glucose on CTL functions still rem...

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Detalles Bibliográficos
Autores principales:	Zhu, Jie, Yang, Wenjuan, Zhou, Xiangda, Zöphel, Dorina, Soriano-Baguet, Leticia, Dolgener, Denise, Carlein, Christopher, Hof, Chantal, Zhao, Renping, Ye, Shandong, Schwarz, Eva C., Brenner, Dirk, Prates Roma, Leticia, Qu, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267470/ https://www.ncbi.nlm.nih.gov/pubmed/34248978 http://dx.doi.org/10.3389/fimmu.2021.689337

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