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High Glucose Enhances Cytotoxic T Lymphocyte-Mediated Cytotoxicity
Cytotoxic T lymphocytes (CTLs) are key players to eliminate tumorigenic or pathogen-infected cells using lytic granules (LG) and Fas ligand (FasL) pathways. Depletion of glucose leads to severely impaired cytotoxic function of CTLs. However, the impact of excessive glucose on CTL functions still rem...
Autores principales: | Zhu, Jie, Yang, Wenjuan, Zhou, Xiangda, Zöphel, Dorina, Soriano-Baguet, Leticia, Dolgener, Denise, Carlein, Christopher, Hof, Chantal, Zhao, Renping, Ye, Shandong, Schwarz, Eva C., Brenner, Dirk, Prates Roma, Leticia, Qu, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267470/ https://www.ncbi.nlm.nih.gov/pubmed/34248978 http://dx.doi.org/10.3389/fimmu.2021.689337 |
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