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Sperm-Specific Glycolysis Enzyme Glyceraldehyde-3-Phosphate Dehydrogenase Regulated by Transcription Factor SOX10 to Promote Uveal Melanoma Tumorigenesis

Melanoma cells exhibit increased aerobic glycolysis, which represents a major biochemical alteration associated with malignant transformation; thus, glycolytic enzymes could be exploited to selectively target cancer cells in cancer therapy. Sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GA...

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Detalles Bibliográficos
Autores principales: Ding, Xia, Wang, Lihua, Chen, Mingjiao, Wu, Yue, Ge, Shengfang, Li, Jin, Fan, Xianqun, Lin, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267526/
https://www.ncbi.nlm.nih.gov/pubmed/34249897
http://dx.doi.org/10.3389/fcell.2021.610683