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Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report

Toxoplasmosis is a rare but potentially severe complication after allogeneic hematopoietic cell transplantation. Toxoplasma gondii-associated cardiac involvement can cause myocarditis, pericarditis, arrhythmias, and congestive heart failure. Most cases with cardiac toxoplasmosis following BMT have b...

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Detalles Bibliográficos
Autores principales: Akella, Padmastuti, Bhatt, Isha, Serhan, Mustapha, Giri, Dilip D., Pastores, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267541/
https://www.ncbi.nlm.nih.gov/pubmed/34277353
http://dx.doi.org/10.1016/j.idcr.2021.e01217
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author Akella, Padmastuti
Bhatt, Isha
Serhan, Mustapha
Giri, Dilip D.
Pastores, Stephen M.
author_facet Akella, Padmastuti
Bhatt, Isha
Serhan, Mustapha
Giri, Dilip D.
Pastores, Stephen M.
author_sort Akella, Padmastuti
collection PubMed
description Toxoplasmosis is a rare but potentially severe complication after allogeneic hematopoietic cell transplantation. Toxoplasma gondii-associated cardiac involvement can cause myocarditis, pericarditis, arrhythmias, and congestive heart failure. Most cases with cardiac toxoplasmosis following BMT have been fatal and diagnosed at autopsy. We present an unfortunate case of sudden onset congestive heart failure symptoms and delayed post-transplant Toxoplasma PCR testing that ultimately led to the diagnosis of cardiac toxoplasmosis on autopsy in our patient.
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spelling pubmed-82675412021-07-16 Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report Akella, Padmastuti Bhatt, Isha Serhan, Mustapha Giri, Dilip D. Pastores, Stephen M. IDCases Case Report Toxoplasmosis is a rare but potentially severe complication after allogeneic hematopoietic cell transplantation. Toxoplasma gondii-associated cardiac involvement can cause myocarditis, pericarditis, arrhythmias, and congestive heart failure. Most cases with cardiac toxoplasmosis following BMT have been fatal and diagnosed at autopsy. We present an unfortunate case of sudden onset congestive heart failure symptoms and delayed post-transplant Toxoplasma PCR testing that ultimately led to the diagnosis of cardiac toxoplasmosis on autopsy in our patient. Elsevier 2021-07-05 /pmc/articles/PMC8267541/ /pubmed/34277353 http://dx.doi.org/10.1016/j.idcr.2021.e01217 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Akella, Padmastuti
Bhatt, Isha
Serhan, Mustapha
Giri, Dilip D.
Pastores, Stephen M.
Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_full Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_fullStr Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_full_unstemmed Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_short Toxic ‘Toxo’ in the heart: Cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
title_sort toxic ‘toxo’ in the heart: cardiac toxoplasmosis following a hematopoietic stem cell transplant- a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267541/
https://www.ncbi.nlm.nih.gov/pubmed/34277353
http://dx.doi.org/10.1016/j.idcr.2021.e01217
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