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A novel amino acid signaling process governs glucose-6-phosphatase transcription
Emerging evidence has shown that amino acids act as metabolic regulatory signals. Here, we showed that glucose-6-phosphatase (G6Pase) mRNA levels in cultured hepatocyte models were downregulated in an amino-acid-depleted medium. Inversely, stimulation with amino acids increased G6Pase mRNA levels, d...
Autores principales: | Fukushima, Sara, Nishi, Hiroki, Kumano, Mikako, Yamanaka, Daisuke, Kataoka, Naoyuki, Hakuno, Fumihiko, Takahashi, Shin-Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267547/ https://www.ncbi.nlm.nih.gov/pubmed/34278273 http://dx.doi.org/10.1016/j.isci.2021.102778 |
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