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A novel amino acid signaling process governs glucose-6-phosphatase transcription

Emerging evidence has shown that amino acids act as metabolic regulatory signals. Here, we showed that glucose-6-phosphatase (G6Pase) mRNA levels in cultured hepatocyte models were downregulated in an amino-acid-depleted medium. Inversely, stimulation with amino acids increased G6Pase mRNA levels, d...

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Detalles Bibliográficos
Autores principales: Fukushima, Sara, Nishi, Hiroki, Kumano, Mikako, Yamanaka, Daisuke, Kataoka, Naoyuki, Hakuno, Fumihiko, Takahashi, Shin-Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267547/
https://www.ncbi.nlm.nih.gov/pubmed/34278273
http://dx.doi.org/10.1016/j.isci.2021.102778

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