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Intracellular Delivery of Doxorubicin by Iron Oxide-Based Nano-Constructs Increases Clonogenic Inactivation of Ionizing Radiation in HeLa Cells

In this study, we determined the potential of polyethylene glycol-encapsulated iron oxide nanoparticles (IONP(CO)) for the intracellular delivery of the chemotherapeutic doxorubicin (IONP(DOX)) to enhance the cytotoxic effects of ionizing radiation. The biological effects of IONP and X-ray irradiati...

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Detalles Bibliográficos
Autores principales: Popescu, Roxana Cristina, Savu, Diana Iulia, Bierbaum, Miriam, Grbenicek, Adriana, Schneider, Frank, Hosser, Hiltraud, Vasile, Bogdan Ștefan, Andronescu, Ecaterina, Wenz, Frederik, Giordano, Frank A., Herskind, Carsten, Veldwijk, Marlon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267614/
https://www.ncbi.nlm.nih.gov/pubmed/34202550
http://dx.doi.org/10.3390/ijms22136778

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