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Intracellular Delivery of Doxorubicin by Iron Oxide-Based Nano-Constructs Increases Clonogenic Inactivation of Ionizing Radiation in HeLa Cells
In this study, we determined the potential of polyethylene glycol-encapsulated iron oxide nanoparticles (IONP(CO)) for the intracellular delivery of the chemotherapeutic doxorubicin (IONP(DOX)) to enhance the cytotoxic effects of ionizing radiation. The biological effects of IONP and X-ray irradiati...
Autores principales: | Popescu, Roxana Cristina, Savu, Diana Iulia, Bierbaum, Miriam, Grbenicek, Adriana, Schneider, Frank, Hosser, Hiltraud, Vasile, Bogdan Ștefan, Andronescu, Ecaterina, Wenz, Frederik, Giordano, Frank A., Herskind, Carsten, Veldwijk, Marlon R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267614/ https://www.ncbi.nlm.nih.gov/pubmed/34202550 http://dx.doi.org/10.3390/ijms22136778 |
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