Proprotein Convertase Subtilisin Kexin Type 9 Inhibitors Reduce Platelet Activation Modulating ox-LDL Pathways

Background: Proprotein convertase subtilisin kexin type 9 inhibitors (PCSK9i) lower LDL-cholesterol and slow atherosclerosis preventing cardiovascular events. While it is known that circulating PCSK9 enhances platelet activation (PA) and that PCSK9i reduce it, the underlying mechanism is not still c...

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Detalles Bibliográficos
Autores principales: Cammisotto, Vittoria, Baratta, Francesco, Castellani, Valentina, Bartimoccia, Simona, Nocella, Cristina, D’Erasmo, Laura, Cocomello, Nicholas, Barale, Cristina, Scicali, Roberto, Di Pino, Antonino, Piro, Salvatore, Del Ben, Maria, Arca, Marcello, Russo, Isabella, Purrello, Francesco, Carnevale, Roberto, Violi, Francesco, Pastori, Daniele, Pignatelli, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267646/
https://www.ncbi.nlm.nih.gov/pubmed/34281247
http://dx.doi.org/10.3390/ijms22137193

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