Cargando…

Quadruplex Ligands in Cancer Therapy

SIMPLE SUMMARY: Four-stranded nucleic acid secondary structures (quadruplexes) including DNA G-quadruplexes, RNA G-quadruplexes and i-Motifs display key regulatory functions in the human genome. Quadruplexes play an important role in telomere lengthening and the expression control of several cancer-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sanchez-Martin, Victoria, Soriano, Miguel, Garcia-Salcedo, Jose Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267697/ https://www.ncbi.nlm.nih.gov/pubmed/34202648 http://dx.doi.org/10.3390/cancers13133156

Ejemplares similares

An Updated Focus on Quadruplex Structures as Potential Therapeutic Targets in Cancer
por: Sanchez-Martin, Victoria, et al.
Publicado: (2020)

Photosensitizers Based on G-Quadruplex Ligand for Cancer Photodynamic Therapy
por: Kawauchi, Keiko, et al.
Publicado: (2020)

G-Quadruplexes and Their Ligands: Biophysical Methods to Unravel G-Quadruplex/Ligand Interactions
por: Santos, Tiago, et al.
Publicado: (2021)

Gallic Acid: A Natural Phenolic Compound Exerting Antitumoral Activities in Colorectal Cancer via Interaction with G-Quadruplexes
por: Sanchez-Martin, Victoria, et al.
Publicado: (2022)

Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy
por: Asamitsu, Sefan, et al.
Publicado: (2019)

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
por: Ruggiero, Emanuela, et al.
Publicado: (2018)

Ligands as Stabilizers of G-Quadruplexes in Non-Coding RNAs
por: Figueiredo, Joana, et al.
Publicado: (2021)

Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands
por: Pirota, Valentina, et al.
Publicado: (2019)

On the Road to Fight Cancer: The Potential of G-Quadruplex Ligands as Novel Therapeutic Agents
por: Alessandrini, Irene, et al.
Publicado: (2021)

Quadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formation
por: Cian, Anne De, et al.
Publicado: (2007)

Ligands stimulating antitumour immunity as the next G-quadruplex challenge
por: Miglietta, Giulia, et al.
Publicado: (2022)

G-Quadruplex Aptamer-Ligand Characterization
por: Moreira, David, et al.
Publicado: (2022)

New Insights on the Interaction of Phenanthroline Based Ligands and Metal Complexes and Polyoxometalates with Duplex DNA and G-Quadruplexes
por: Sánchez-González, Ángel, et al.
Publicado: (2021)

Promise of G-Quadruplex Structure Binding Ligands as Epigenetic Modifiers with Anti-Cancer Effects
por: Sengupta, Antara, et al.
Publicado: (2019)

Natural Alkaloids and Heterocycles as G-Quadruplex Ligands and Potential Anticancer Agents
por: Che, Tong, et al.
Publicado: (2018)

Small-Molecule-Based Self-Assembled Ligands for G-Quadruplex DNA Surface Recognition
por: Rivera-Sánchez, María del C., et al.
Publicado: (2017)

Fluorescence-based duplex–quadruplex competition test to screen for telomerase RNA quadruplex ligands
por: Lacroix, Laurent, et al.
Publicado: (2011)

Characterization of G-Quadruplexes in Enterovirus A71 Genome and Their Interaction with G-Quadruplex Ligands
por: Lv, Lu, et al.
Publicado: (2022)

G-quadruplexes: a promising target for cancer therapy
por: Kosiol, Nils, et al.
Publicado: (2021)

Stability of Human Telomeric G-Quadruplexes Complexed with Photosensitive Ligands and Irradiated with Visible Light
por: Libera, Valeria, et al.
Publicado: (2023)

G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications
por: Umar, Mubarak I., et al.
Publicado: (2019)

Detection of CpG Methylation in G-Quadruplex Forming Sequences Using G-Quadruplex Ligands
por: Hasegawa, Hijiri, et al.
Publicado: (2021)

BrdU immuno-tagged G-quadruplex ligands: a new ligand-guided immunofluorescence approach for tracking G-quadruplexes in cells
por: Masson, Thibaut, et al.
Publicado: (2021)

G-Quadruplex-Based Drug Delivery Systems for Cancer Therapy
por: Lopes-Nunes, Jéssica, et al.
Publicado: (2021)

G-Quadruplexes in c-MYC Promoter as Targets for Cancer Therapy
por: Bahls, Bárbara, et al.
Publicado: (2023)

Exploring the Relationship between G-Quadruplex Nucleic Acids and Plants: From Plant G-Quadruplex Function to Phytochemical G4 Ligands with Pharmaceutic Potential
por: Falanga, Andrea P., et al.
Publicado: (2022)

Reprogramming the Mechanism of Action of Chlorambucil by Coupling to a G-Quadruplex Ligand
por: Di Antonio, Marco, et al.
Publicado: (2014)

Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells
por: Carvalho, Josué, et al.
Publicado: (2019)

Insights from Binding on Quadruplex Selective Carbazole Ligands
por: Müller, Diana, et al.
Publicado: (2021)

Mechanistic insight into ligand binding to G-quadruplex DNA
por: Di Leva, Francesco Saverio, et al.
Publicado: (2014)

Xanthene and Xanthone Derivatives as G-Quadruplex Stabilizing Ligands
por: Altieri, Alessandro, et al.
Publicado: (2013)

Indoloquinoline Ligands Favor Intercalation at Quadruplex‐Duplex Interfaces
por: Vianney, Yoanes Maria, et al.
Publicado: (2022)

Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance
por: Wang, Shi-Ke, et al.
Publicado: (2015)

Replication Control of Human Telomere G-Quadruplex DNA by G-Quadruplex Ligands Dependent on Solution Environment
por: Takahashi, Shuntaro, et al.
Publicado: (2022)

Using Macrocyclic G‐Quadruplex Ligands to Decipher the Interactions Between Small Molecules and G‐Quadruplex DNA
por: Andréasson, Måns, et al.
Publicado: (2022)

G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents
por: Belmonte-Reche, Efres, et al.
Publicado: (2018)

opp-Dibenzoporphyrin Pyridinium Derivatives as Potential G-Quadruplex DNA Ligands
por: Moura, Nuno M. M., et al.
Publicado: (2023)

Dual Targeting Topoisomerase/G-Quadruplex Agents in Cancer Therapy—An Overview
por: Salerno, Silvia, et al.
Publicado: (2022)

Recent Developments in Small-Molecule Ligands of Medicinal Relevance for Harnessing the Anticancer Potential of G-Quadruplexes
por: Savva, Loukiani, et al.
Publicado: (2021)

Metal-Based G-Quadruplex Binders for Cancer Theranostics
por: Palma, Elisa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_og3ansre52o4u8ntl36p07gm63