Cargando…
Methotrexate Neurotoxicity Is Related to Epigenetic Modification of the Myelination Process
With the improvement of the survival rate of acute lymphoblastic leukemia (ALL) in children, some children ALL survivors reveal inferior intellectual and cognition outcome. Methotrexate (MTX), while serving as an essential component in ALL treatment, has been reported to be related to various neurol...
Autores principales: | Chen, Yu-Chieh, Sheen, Jiunn-Ming, Wang, Su-Chen, Hsu, Mei-Hsin, Hsiao, Chih-Cheng, Chang, Kow-Aung, Huang, Li-Tung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8267729/ https://www.ncbi.nlm.nih.gov/pubmed/34201550 http://dx.doi.org/10.3390/ijms22136718 |
Ejemplares similares
-
Maternal Obesity Programs Offspring Development and Resveratrol Potentially Reprograms the Effects of Maternal Obesity
por: Hsu, Mei-Hsin, et al.
Publicado: (2020) -
Melatonin prevented spatial deficits and increases in brain asymmetric dimethylarginine in young bile duct ligation rats
por: Hsu, Mei-Hsin, et al.
Publicado: (2018) -
Increased Circulating ADMA in Young Male Rats Caused Cognitive Deficits and Increased Intestinal and Hippocampal NLRP3 Inflammasome Expression and Microbiota Composition Alterations: Effects of Resveratrol
por: Hsu, Mei-Hsin, et al.
Publicado: (2023) -
The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia
por: Ma, Lin-Hui, et al.
Publicado: (2022) -
Combined Intraperitoneal and Intrathecal Etanercept Reduce Increased Brain Tumor Necrosis Factor-Alpha and Asymmetric Dimethylarginine Levels and Rescues Spatial Deficits in Young Rats after Bile Duct Ligation
por: Sheen, Jiunn-Ming, et al.
Publicado: (2016)